发明申请
US20070243565A1 LUMINESCENCE RESONANCE ENERGY TRANSFER (LRET) ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY
有权
光合能力转移(LRET)用于离子毒素活性的测定
- 专利标题: LUMINESCENCE RESONANCE ENERGY TRANSFER (LRET) ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY
- 专利标题(中): 光合能力转移(LRET)用于离子毒素活性的测定
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申请号: US11752596申请日: 2007-05-23
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公开(公告)号: US20070243565A1公开(公告)日: 2007-10-18
- 发明人: Dudley Williams , Marcella Gilmore , Lance Steward , Marc Verhagen , Kei Aoki , Ester Fernandez-Salas
- 申请人: Dudley Williams , Marcella Gilmore , Lance Steward , Marc Verhagen , Kei Aoki , Ester Fernandez-Salas
- 主分类号: G01N33/554
- IPC分类号: G01N33/554 ; C07H19/00 ; C12N1/20 ; C12N15/00
摘要:
Clostridial toxin substrates comprising a lanthanide donor complex, an acceptor, and a Clostridial toxin recognition sequence including a cleavage site; methods for determining the activity of a Clostridial toxin from a test sample using such Clostridial toxin substrates; cell compositions comprising such Clostridial toxin substrates and a Clostridial toxin receptor; and methods for determining the activity of a Clostridial toxin from a test sample using such cell compositions.
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