发明申请
US20080050745A1 Sugar chain synthesizing agent having beta1,3-N-acetyglucosaminyltransferase activity
有权
具有β1,3-N-乙酰氨基葡糖基转移酶活性的糖链合成剂
- 专利标题： Sugar chain synthesizing agent having beta1,3-N-acetyglucosaminyltransferase activity
- 专利标题（中）： 具有β1,3-N-乙酰氨基葡糖基转移酶活性的糖链合成剂
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申请号： US11837804申请日： 2007-08-13
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公开(公告)号： US20080050745A1公开(公告)日： 2008-02-28
- 发明人: Hisashi Narimatsu , Katsutoshi Sasaki , Ayumi Natsume , Hiroyuki Mio , Satoshi Nakagawa , Susumu Sekine , Akira Togayachi
- 申请人： Hisashi Narimatsu , Katsutoshi Sasaki , Ayumi Natsume , Hiroyuki Mio , Satoshi Nakagawa , Susumu Sekine , Akira Togayachi
- 申请人地址： JP Chiyoda-ku
- 专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人地址： JP Chiyoda-ku
- 优先权： JP2000-265430 20000901
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; A01K67/00 ; C07H21/04 ; C12N1/00 ; C12N15/54 ; C12N5/10 ; G01N33/53 ; C12N9/10 ; C12N9/99 ; C12P19/04 ; C12P21/00
摘要：
The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.
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