发明申请
US20080118952A1 Polynucelotides encoding novel variants of the TRP channel family member, LTRPC3
有权
Polynucelotides编码TRP通道家族成员LTRPC3的新型变体
- 专利标题: Polynucelotides encoding novel variants of the TRP channel family member, LTRPC3
- 专利标题(中): Polynucelotides编码TRP通道家族成员LTRPC3的新型变体
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申请号: US11985981申请日: 2007-11-19
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公开(公告)号: US20080118952A1公开(公告)日: 2008-05-22
- 发明人: Ning Lee , Jian Chen , John Feder , Shujian Wu , Michael Blanar , David Bol , Paul Levesque , Lucy Sun
- 申请人: Ning Lee , Jian Chen , John Feder , Shujian Wu , Michael Blanar , David Bol , Paul Levesque , Lucy Sun
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 主分类号: C12P21/04
- IPC分类号: C12P21/04 ; C07K16/00
摘要:
The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
公开/授权文献
- US07459532B2 Variants of the TRP channel family member, LTRPC3G 公开/授权日:2008-12-02
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