发明申请
US20080213247A1 Mbms as Modifiers of Branching Morphogenesis and Methods of Use
审中-公开
Mbms作为分支形态发生的修饰剂和使用方法
- 专利标题: Mbms as Modifiers of Branching Morphogenesis and Methods of Use
- 专利标题(中): Mbms作为分支形态发生的修饰剂和使用方法
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申请号: US10532547申请日: 2003-10-22
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公开(公告)号: US20080213247A1公开(公告)日: 2008-09-04
- 发明人: Gregory D. Plowman , Felix D. Karim , Candace Swimmer , Hinrich Alexander Habeck , Thomas I. Koblizek , Stefan Schulte-Merker , Ulrike Langheinrich , Gordon Mark Stott , Torsten Trowe , Andreas Michael Vogel , Joerg Heinrich Odenthal , Jochen Konrad Scheel , Torsten Tilmann Will , Yisheng Jin , Lynn Margaret Bjerke , Bing Hai , Joanne I. Adamkewicz , Kim Licketeig , R. Glenn R. Hammonds , Craig D. Amundsen , Haiguang Zhang , Monique Nicoll
- 申请人: Gregory D. Plowman , Felix D. Karim , Candace Swimmer , Hinrich Alexander Habeck , Thomas I. Koblizek , Stefan Schulte-Merker , Ulrike Langheinrich , Gordon Mark Stott , Torsten Trowe , Andreas Michael Vogel , Joerg Heinrich Odenthal , Jochen Konrad Scheel , Torsten Tilmann Will , Yisheng Jin , Lynn Margaret Bjerke , Bing Hai , Joanne I. Adamkewicz , Kim Licketeig , R. Glenn R. Hammonds , Craig D. Amundsen , Haiguang Zhang , Monique Nicoll
- 国际申请: PCT/US03/33549 WO 20031022
- 主分类号: G01N33/00
- IPC分类号: G01N33/00 ; C12Q1/48 ; C12Q1/68 ; G01N33/50 ; A61K39/395 ; C12Q1/02 ; A61P35/00
摘要:
Human MBM genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MBM are provided.
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