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发明申请
US20090069327A1 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS 审中-公开
作为蛋白激酶抑制剂的化合物和组合物

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, Bmx, b-RAF, c-RAF, c-SRC, KDR, CSK, FGFR3, JAK2, Lck, Met, PKCα, SAPK2α, Tie2, TrkB and P70S6K kinases.
摘要（中）：

本发明提供了一类新颖的化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的激酶活性相关的疾病或病症的方法，特别是涉及Abl，Bcr-Abl异常活化的疾病或病症 ，Bmx，b-RAF，c-RAF，c-SRC，KDR，CSK，FGFR3，JAK2，Lck，Met，PKCalpha，SAPK2alpha，Tie2，TrkB和P70S6K激酶。

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