发明申请
US20090215728A1 Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, medicaments comprising these compounds, and their use
有权
芳基氨基芳基 - 烷基取代的咪唑烷-2,4-二酮，其制备方法，包含这些化合物的药物及其用途
- 专利标题： Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, medicaments comprising these compounds, and their use
- 专利标题（中）： 芳基氨基芳基 - 烷基取代的咪唑烷-2,4-二酮，其制备方法，包含这些化合物的药物及其用途
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申请号： US12365940申请日： 2009-02-05
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公开(公告)号： US20090215728A1公开(公告)日： 2009-08-27
- 发明人: Gerhard JAEHNE , Siegfried STENGELIN , Matthias GOSSEL , Thomas KLABUNDE , Irvin WINKLER
- 申请人： Gerhard JAEHNE , Siegfried STENGELIN , Matthias GOSSEL , Thomas KLABUNDE , Irvin WINKLER
- 申请人地址： FR Paris
- 专利权人： SANOFI-AVENTIS
- 当前专利权人： SANOFI-AVENTIS
- 当前专利权人地址： FR Paris
- 优先权： DE102006036930.0 20060808; DE102006040592.7 20060830
- 主分类号： A61K31/675
- IPC分类号： A61K31/675 ; C07D233/76 ; A61K31/4174 ; A61K31/4439 ; C07D401/12 ; C07F9/6506 ; A61P3/10
摘要：
This invention relates to arylaminoaryl-alkyl-substituted imidazolidone-2,4-diones of formula (I) and also to their physiologically tolerated salts: Wherein R, R′, R1 to R10, A, D, E, G, L and p are as defined herein. The invention also relates to processes for preparing them, pharmaceutical compositions comprising them and their therapeutic use. The compounds are suitable, for example, as anti-obesity drugs and for treating cardiometabolic syndrome.