发明申请
US20090317428A1 Immunogenic T-Helper Epitopes From Human Tumour Antigens and Immunotherapeutic Methods Using Said Epitopes
失效
来自人肿瘤抗原的免疫原性T辅助表位和使用所述表位的免疫治疗方法
- 专利标题： Immunogenic T-Helper Epitopes From Human Tumour Antigens and Immunotherapeutic Methods Using Said Epitopes
- 专利标题（中）： 来自人肿瘤抗原的免疫原性T辅助表位和使用所述表位的免疫治疗方法
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申请号： US11664627申请日： 2005-09-09
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公开(公告)号： US20090317428A1公开(公告)日： 2009-12-24
- 发明人: Hans-Georg Rammensee , Toni Weinschenk , Jörn Dengjel
- 申请人： Hans-Georg Rammensee , Toni Weinschenk , Jörn Dengjel
- 专利权人： Immatics Biotechnologies GmbH
- 当前专利权人： Immatics Biotechnologies GmbH
- 优先权： EP04023546.7 20041002
- 国际申请： PCT/EP2005/009719 WO 20050909
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K35/12 ; C12P21/00 ; C12N5/00 ; C12N15/63 ; A61K38/16 ; A61K38/10 ; A61K38/08 ; A61K31/7052 ; C07K2/00 ; C07K14/00 ; C07K7/08 ; A61P37/04 ; C07K7/06 ; A61P35/00 ; C07H21/00
摘要：
The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular renal cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 338 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.
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