发明申请
US20100172878A1 Polynucleotides encoding mhc class i-restricted htert epitopes, analogues thereof or polyepitopes
有权
编码mhc类i限制性hTERT表位的多核苷酸，其类似物或多表位
- 专利标题： Polynucleotides encoding mhc class i-restricted htert epitopes, analogues thereof or polyepitopes
- 专利标题（中）： 编码mhc类i限制性hTERT表位的多核苷酸，其类似物或多表位
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申请号： US11795027申请日： 2006-07-31
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公开(公告)号： US20100172878A1公开(公告)日： 2010-07-08
- 发明人: Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut
- 申请人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut
- 优先权： EP05291627.7 20050729
- 国际申请： PCT/EP2006/007571 WO 20060731
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; C12N15/54 ; C12N15/63 ; C12N5/07 ; C12N9/12 ; A61K31/7052 ; A61K38/45 ; C12N5/0783 ; C12Q1/02 ; C12N15/00 ; A61P35/00 ; A61P37/04
摘要：
This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogues thereof and polyepitopes containing such epitopes and/or analogues. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
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