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1.发明授权Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes 有权编码MHC I类限制性hTERT表位的多核苷酸，其类似物或多表位公开(公告)号：US08003773B2
公开(公告)日：2011-08-23
申请号：US11826134
申请日：2007-07-12
申请人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut , Kostas Kosmatopoulos , Stéphanie Graff-Dubois , Jeanne Menez-Jamet
发明人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut , Kostas Kosmatopoulos , Stéphanie Graff-Dubois , Jeanne Menez-Jamet
CPC分类号： C12N9/1276 , A61K38/00 , A61K39/0011 , A61K2039/572 , C12N9/1241
摘要： This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogues thereof and polyepitopes containing such epitopes and/or analogues. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
摘要翻译： 本发明涉及抗癌治疗领域，以及鉴定源自人端粒酶逆转录酶（hTERT）的免疫原性肽。 本发明涉及编码限于MHC I类分子的hTERT表位的多核苷酸，其类似物和含有这些表位和/或类似物的多表位。 也包括在本发明中，包含这种多核苷酸的载体和细胞。 本发明还涉及包含用于治疗和/或预防癌症的hTERT多肽，相应的多核苷酸，载体和细胞的组合物。
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2.发明申请Polynucleotides encoding mhc class i-restricted htert epitopes, analogues thereof or polyepitopes 有权编码mhc类i限制性hTERT表位的多核苷酸，其类似物或多表位公开(公告)号：US20100172878A1
公开(公告)日：2010-07-08
申请号：US11795027
申请日：2006-07-31
申请人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut
发明人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut
IPC分类号： A61K35/12 , C12N15/54 , C12N15/63 , C12N5/07 , C12N9/12 , A61K31/7052 , A61K38/45 , C12N5/0783 , C12Q1/02 , C12N15/00 , A61P35/00 , A61P37/04
CPC分类号： C12N9/1276 , A61K38/00 , A61K39/0011 , A61K2039/572 , C12N9/1241
摘要： This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogues thereof and polyepitopes containing such epitopes and/or analogues. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
摘要翻译： 本发明涉及抗癌治疗领域，以及鉴定源自人端粒酶逆转录酶（hTERT）的免疫原性肽。 本发明涉及编码限于MHC I类分子的hTERT表位的多核苷酸，其类似物和含有这些表位和/或类似物的多表位。 也包括在本发明中，包含这种多核苷酸的载体和细胞。 本发明还涉及包含用于治疗和/或预防癌症的hTERT多肽，相应的多核苷酸，载体和细胞的组合物。
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3.发明授权Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes 有权编码MHC I类限制性hTERT表位的多核苷酸，其类似物或多表位公开(公告)号：US08858931B2
公开(公告)日：2014-10-14
申请号：US11795027
申请日：2006-07-31
申请人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut
发明人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Sylvain Cardinaud , Christine Neuveut
CPC分类号： C12N9/1276 , A61K38/00 , A61K39/0011 , A61K2039/572 , C12N9/1241
摘要： This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogs thereof and polyepitopes containing such epitopes and/or analogs. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
摘要翻译： 本发明涉及抗癌治疗领域，以及鉴定源自人端粒酶逆转录酶（hTERT）的免疫原性肽。 本发明涉及编码限于MHC I类分子的hTERT表位的多核苷酸，其类似物和含有这些表位和/或类似物的多表位。 也包括在本发明中，包含这种多核苷酸的载体和细胞。 本发明还涉及包含用于治疗和/或预防癌症的hTERT多肽，相应的多核苷酸，载体和细胞的组合物。
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4.发明申请Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes 有权编码MHC I类限制性hTERT表位的多核苷酸，其类似物或多表位公开(公告)号：US20090175892A1
公开(公告)日：2009-07-09
申请号：US11826134
申请日：2007-07-12
申请人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Syvain Cardinaud , Christine Neuveut , Kostas Kosmatopoulos , Stephanie Graff-Dubois , Jeanne Menez-Jamet
发明人： Pierre Langlade-Demoyen , Fransisco Garcia Pons , Olivier Adotevi , Syvain Cardinaud , Christine Neuveut , Kostas Kosmatopoulos , Stephanie Graff-Dubois , Jeanne Menez-Jamet
IPC分类号： A61K39/00 , C12N15/11 , C12N15/00 , C12N5/06 , C12N5/08 , C12N9/00 , A61K31/7088 , A61K35/12
CPC分类号： C12N9/1276 , A61K38/00 , A61K39/0011 , A61K2039/572 , C12N9/1241
摘要： This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogues thereof and polyepitopes containing such epitopes and/or analogues. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
摘要翻译： 本发明涉及抗癌治疗领域，以及鉴定源自人端粒酶逆转录酶（hTERT）的免疫原性肽。 本发明涉及编码限于MHC I类分子的hTERT表位的多核苷酸，其类似物和含有这些表位和/或类似物的多表位。 也包括在本发明中，包含这种多核苷酸的载体和细胞。 本发明还涉及包含用于治疗和/或预防癌症的hTERT多肽，相应的多核苷酸，载体和细胞的组合物。
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