发明申请
- 专利标题: FUSED BICYCLIC PYRIMIDINES
- 专利标题(中): 熔融双相PYRIMIDINES
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申请号: US12731880申请日: 2010-03-25
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公开(公告)号: US20100184782A1公开(公告)日: 2010-07-22
- 发明人: Swen Hölder , Matthias Vennemann , Gerrit Beneke , Armin Zülch , Volker Gekeler , Thomas Beckers , Astrid Zimmermann , Hemant Joshi
- 申请人: Swen Hölder , Matthias Vennemann , Gerrit Beneke , Armin Zülch , Volker Gekeler , Thomas Beckers , Astrid Zimmermann , Hemant Joshi
- 优先权: IN1572/MUM/2007 20070814; EP07118736.3-2117 20071018
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61P35/00 ; A61P35/02
摘要:
Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
公开/授权文献
- US08614218B2 Fused bicyclic pyrimidines 公开/授权日:2013-12-24