发明申请
US20110065686A1 CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES
有权
具有针对登革病毒和其他感染病毒的抗病毒活性的化学化合物
- 专利标题： CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES
- 专利标题（中）： 具有针对登革病毒和其他感染病毒的抗病毒活性的化学化合物
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申请号： US12919416申请日： 2009-02-27
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公开(公告)号： US20110065686A1公开(公告)日： 2011-03-17
- 发明人: Yuliet Mazola Reyes , Glay Chinea Santiago , Osmany Guirola Cruz , Roberto Vera Alvarez , Vivian Huerta Galindo , Noralvis Fleitas Salazar , Alexis Musacchio Lasa
- 申请人： Yuliet Mazola Reyes , Glay Chinea Santiago , Osmany Guirola Cruz , Roberto Vera Alvarez , Vivian Huerta Galindo , Noralvis Fleitas Salazar , Alexis Musacchio Lasa
- 优先权： CU2008-0028 20080229
- 国际申请： PCT/CU2009/000002 WO 20090227
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; C12Q1/70 ; A61K31/18 ; A61K31/36 ; A61K31/4965 ; A61K31/34 ; A61K31/38 ; A61K31/445 ; A61K31/5375 ; A61K31/50 ; A61K31/505 ; A61K31/428 ; A61K31/5377 ; A61P31/12
摘要：
Use of chemical compounds obtained in silico for the preparation of pharmaceutical compositions to attenuate or inhibit Dengue virus infection. Particularly, through the interference or the modulation of several stages of viral replication cycle related with the entry of virus into host cells and the assembly of mature progeny virions. The invention also comprises the use of such pharmaceutical compositions for prophylactic and/or therapeutic treatment of infection caused by all four serotypes of Dengue virus and other flaviviruses.
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