发明申请
US20110318730A1 MICROPATTERNED CO-CULTURE SYSTEMS AS INFECTIOUS DISEASE ANALYSIS PLATFORMS
审中-公开
微生物共培养系统作为感染性疾病分析平台
- 专利标题: MICROPATTERNED CO-CULTURE SYSTEMS AS INFECTIOUS DISEASE ANALYSIS PLATFORMS
- 专利标题(中): 微生物共培养系统作为感染性疾病分析平台
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申请号: US13003214申请日: 2009-07-07
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公开(公告)号: US20110318730A1公开(公告)日: 2011-12-29
- 发明人: Charles M. Rice, III , Christopher Thomas Jones , Alexander Ploss , Sangeeta N. Bhatia , Salman Khetani
- 申请人: Charles M. Rice, III , Christopher Thomas Jones , Alexander Ploss , Sangeeta N. Bhatia , Salman Khetani
- 申请人地址: US NY New York US MA Cambridge
- 专利权人: THE ROCKEFELLER UNIVERSITY,MASS INSTITUTE OF TECHNOLOGY
- 当前专利权人: THE ROCKEFELLER UNIVERSITY,MASS INSTITUTE OF TECHNOLOGY
- 当前专利权人地址: US NY New York US MA Cambridge
- 国际申请: PCT/US2009/049849 WO 20090707
- 主分类号: C12Q1/02
- IPC分类号: C12Q1/02 ; G01N33/53 ; C12Q1/68 ; C12N5/071 ; C12N5/077
摘要:
Cell cultures are provided that include a population of micropatterened hepatocytes and one or more non-parenchymal cell populations, where the hepatocytes are infected with a virus or parasite and include a reporter of virus or parasite infection. Methods of making and using the cell cultures are also provided.