发明申请
- 专利标题: 1-HYDROXYIMINO-3-PHENYL-PROPANES
- 专利标题(中): 1-羟基亚氨基-3-苯基丙酸酯
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申请号: US13180574申请日: 2011-07-12
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公开(公告)号: US20120010190A1公开(公告)日: 2012-01-12
- 发明人: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
- 申请人: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
- 优先权: EP10169293.7 20100712
- 主分类号: A61K31/4409
- IPC分类号: A61K31/4409 ; C07D401/10 ; A61K31/506 ; C07D413/10 ; A61P3/10 ; A61K31/4427 ; C07D417/10 ; A61P3/00 ; A61P29/00 ; C07D213/53 ; A61K31/5377
摘要:
This invention relates to novel 1-hydroxyimino-3-phenyl-propanes of the formula wherein R1 to R10 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and may be used as medicaments for the treatment of diseases such as type II diabetes.
公开/授权文献
- US08765730B2 1-hydroxyimino-3-phenyl-propanes 公开/授权日:2014-07-01
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