Invention Application
US20120014975A1 MODIFIED SINGLE DOMAIN ANTIGEN BINDING MOLECULES AND USES THEREOF
审中-公开
改良的单抗抗原结合分子及其用途
- Patent Title: MODIFIED SINGLE DOMAIN ANTIGEN BINDING MOLECULES AND USES THEREOF
- Patent Title (中): 改良的单抗抗原结合分子及其用途
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Application No.: US13182560Application Date: 2011-07-14
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Publication No.: US20120014975A1Publication Date: 2012-01-19
- Inventor: Martin Hegen , Stephane Hubert Olland , Yulia Vugmeyster , Xin Xu
- Applicant: Martin Hegen , Stephane Hubert Olland , Yulia Vugmeyster , Xin Xu
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Main IPC: A61K47/48
- IPC: A61K47/48 ; G01N33/53 ; A61B19/00 ; A61P29/00 ; A61P37/06 ; G01N33/566 ; C07K17/08 ; A61K49/00
Abstract:
The invention relates to modified single domain antigen binding molecules, e.g., SDAB molecules, in particular TNFα-binding SDAB molecules. Method of preparing, and using the modified single domain antigen binding molecules described herein, to treat, e.g., TNFα-associated disorders, are also disclosed.
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