公开(公告)号：US20120014975A1

公开(公告)日：2012-01-19

申请号：US13182560

申请日：2011-07-14

申请人： Martin Hegen ,  Stephane Hubert Olland ,  Yulia Vugmeyster ,  Xin Xu

发明人： Martin Hegen ,  Stephane Hubert Olland ,  Yulia Vugmeyster ,  Xin Xu

IPC分类号： A61K47/48 ,  G01N33/53 ,  A61B19/00 ,  A61P29/00 ,  A61P37/06 ,  G01N33/566 ,  C07K17/08 ,  A61K49/00

CPC分类号： C07K16/241 ,  A61K47/60 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/40 ,  C07K2317/569 ,  C07K2317/76 ,  C07K2317/90 ,  C07K2317/92

摘要： The invention relates to modified single domain antigen binding molecules, e.g., SDAB molecules, in particular TNFα-binding SDAB molecules. Method of preparing, and using the modified single domain antigen binding molecules described herein, to treat, e.g., TNFα-associated disorders, are also disclosed.

摘要翻译： 本发明涉及修饰的单结构域抗原结合分子，例如SDAB分子，特别是TNFα结合的SDAB分子。 还公开了制备和使用本文所述的修饰的单结构域抗原结合分子来治疗例如TNFα相关疾病的方法。

公开(公告)号：US20090068195A1

公开(公告)日：2009-03-12

申请号：US12107456

申请日：2008-04-22

申请人： Yulia Vugmeyster ,  Xin Xu ,  Xianbin Tian ,  Donald G. Raible ,  Yuji Simon Zhou ,  Billie Durn

发明人： Yulia Vugmeyster ,  Xin Xu ,  Xianbin Tian ,  Donald G. Raible ,  Yuji Simon Zhou ,  Billie Durn

IPC分类号： A61K39/395 ,  G06F19/00 ,  A61P11/00 ,  A61P29/00 ,  A61P35/00

CPC分类号： C07K16/244 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  G01N33/6854 ,  Y02A90/26

摘要： Methods and compositions for reducing or inhibiting, or preventing or delaying the onset of, one or more symptoms associated with an early and/or a late phase of an IL-13-associated disorder or condition using IL-13 binding agents are disclosed. Methods for evaluating the kinetics and/or efficacy of an IL-13 binding agent in treating or preventing an IL-13-associated disorder or condition in a subject, e.g., a human subject, are also disclosed.

摘要翻译： 公开了用于减少或抑制或预防或延迟与IL-13相关疾病或病症的早期和/或晚期相关的一种或多种症状的使用IL-13结合剂的方法和组合物。 还公开了用于评价IL-13结合剂在治疗或预防受试者例如人受试者中的IL-13相关障碍或病症的动力学和/或功效的方法。

公开(公告)号：US10670566B2

公开(公告)日：2020-06-02

申请号：US15777750

申请日：2016-11-18

申请人： Wan Y. Shih ,  Wei-Heng Shih ,  Christopher Emery ,  Xin Xu ,  Suresh Joshi ,  Wei Wu

发明人： Wan Y. Shih ,  Wei-Heng Shih ,  Christopher Emery ,  Xin Xu ,  Suresh Joshi ,  Wei Wu

IPC分类号： C12Q1/18 ,  G01N29/12 ,  G01N29/036 ,  G01N29/02

摘要： A system for and method of antimicrobial susceptibility testing includes detecting a resonance peak of a sensor provided with live microbes on a surface thereof; applying a substance to the live microbes; detecting a resonance peak of said sensor after application of said substance; determining a width of a top of each of said resonance peaks before and after application of the substance from one of: (1) a phase angle versus frequency plot where the phase angle is the phase angle of the electrical impedance of said sensor. (2) a real part of a plot of an electrical impedance versus frequency of said sensor. (3) a plot of a magnitude of electrical impedance versus frequency of said sensor, and (4) a phase angle versus frequency plot where the phase angle is the phase angle between an output voltage and an input voltage of said sensor, and comparing the determined widths of tops of said resonance peaks or standard deviations of the frequency of said resonance peaks to determine antimicrobial susceptibility including the minimum inhibitory concentration (MIC).

公开(公告)号：US10357196B2

公开(公告)日：2019-07-23

申请号：US15109860

申请日：2015-01-07

申请人： Wan Y. Shih ,  Wei-Heng Shih ,  Xin Xu

发明人： Wan Y. Shih ,  Wei-Heng Shih ,  Xin Xu

IPC分类号： A61B5/00 ,  A61B5/107

摘要： An apparatus and method for determining the depth of an object below a surface or the thickness of the dermis. The apparatus and method use a plurality of piezoelectric fingers having probes with differently sized contact areas. A plurality of measurements is taken using each of the probes with differently sized contact areas in order to determine the depth of an object below a surface or the thickness of the dermis.

公开(公告)号：US20120239609A1

公开(公告)日：2012-09-20

申请号：US13047573

申请日：2011-03-14

申请人： Jie Zhao ,  Bin Dong ,  Yingyu Chen ,  Xin Xu

发明人： Jie Zhao ,  Bin Dong ,  Yingyu Chen ,  Xin Xu

IPC分类号： G06F17/30

CPC分类号： G06F17/30292 ,  G06Q10/0637

摘要： In one embodiment the present invention includes a computer implemented method of relating data and generating reports. The method includes storing, by an OLAP system, a network data structure that relates a plurality of data objects. The method further includes storing transactional data in an in-memory database in the OLAP system. The method further includes generating, by the OLAP system, a report using the stored transactional data according to the network data structure. In this manner, deficiencies of the traditional star schema paradigm of data warehousing may be avoided.

摘要翻译： 在一个实施例中，本发明包括一种将数据和生成报告相关联的计算机实现的方法。 该方法包括通过OLAP系统存储涉及多个数据对象的网络数据结构。 该方法还包括将事务数据存储在OLAP系统中的存储器内数据库中。 该方法还包括根据网络数据结构，通过OLAP系统生成使用存储的事务数据的报告。 以这种方式，可以避免数据仓库的传统星型模式范例的缺陷。

公开(公告)号：US08065252B2

公开(公告)日：2011-11-22

申请号：US12358513

申请日：2009-01-23

申请人： Yi-Zhang Li ,  Zhen-Hua Wang ,  Yuan-Yu Chen ,  Xin Xu ,  Chao Su

发明人： Yi-Zhang Li ,  Zhen-Hua Wang ,  Yuan-Yu Chen ,  Xin Xu ,  Chao Su

IPC分类号： G06F17/00 ,  G06N5/00 ,  G06G7/48

CPC分类号： G06F17/50 ,  G06F2217/02

摘要： The present invention relates to an engineering design method and a system of implementing same. In one embodiment, the method includes a construction process of knowledge components and a design process based on the knowledge components. The knowledge components pack universal modules in the standard forms. Accordingly, the knowledge components are independent from design layouts or design processes of products, and reusable in different projects and platforms. The design process integrates a variety of software platforms via an uniform environment and calls the knowledge components to complete the engineering designs. Further, the design process defines a data relation and an execution relation of the knowledge components and establishes a relationship between the knowledge components without programming. The universal module comprises at least operations, methods, rules and/or flows of an engineering design process and engineering analysis process.

摘要翻译： 本发明涉及一种工程设计方法及其实现方法。 在一个实施例中，该方法包括基于知识组件的知识组件的构造过程和设计过程。 知识组件以标准形式包装通用模块。 因此，知识组件独立于产品的设计布局或设计过程，并可在不同的项目和平台中重用。 设计过程通过统一的环境集成了各种软件平台，并调用知识组件来完成工程设计。 此外，设计过程定义知识组件的数据关系和执行关系，并且在没有编程的情况下建立知识组件之间的关系。 通用模块至少包括工程设计过程和工程分析过程的操作，方法，规则和/或流程。

公开(公告)号：US08013266B2

公开(公告)日：2011-09-06

申请号：US12407163

申请日：2009-03-19

申请人： Xin Xu

发明人： Xin Xu

IPC分类号： H01H3/12

CPC分类号： H04M1/23 ,  H04M1/57 ,  H04M19/04 ,  H04M19/047

摘要： A portable electronic device is provided. The portable electronic device includes the keypad assembly. The keypad assembly includes key buttons. The key button includes a circuit board portion; a pad portion made of elastic material and fixed on the circuit board portion; a supporting portion forming a cavity and connecting to the circuit board portion; a key portion slidably positioned on the supporting portion and forming a containing area between the key portion and supporting portion; and a vibrating portion contained in the cavity formed by the supporting portion and the containing area, the vibrating portion being powered by the circuit board portion, such that when the vibrating portion is powered on and off, the vibrating portion vibrates and makes the key portion slide along the supporting portion.

摘要翻译： 提供便携式电子设备。 便携式电子设备包括键盘组件。 键盘组件包括按键。 键按钮包括电路板部分; 由弹性材料制成并固定在电路板部分上的焊盘部分; 形成空腔并连接到电路板部分的支撑部分; 可滑动地定位在支撑部分上并在键部分和支撑部分之间形成容纳区域的键部分; 以及包含在由所述支撑部和所述容纳区域形成的所述空腔中的振动部，所述振动部由所述电路基板部分供电，使得当所述振动部分被通电和断开时，所述振动部分振动并使所述键部分 沿着支撑部分滑动。

公开(公告)号：US07821983B2

公开(公告)日：2010-10-26

申请号：US11002145

申请日：2004-12-03

申请人： He Wang ,  Xin Xu ,  Xingjie Fan ,  Luoning Gui

发明人： He Wang ,  Xin Xu ,  Xingjie Fan ,  Luoning Gui

IPC分类号： H04W4/00

CPC分类号： H04W72/0486 ,  H04W28/18 ,  H04W28/24

摘要： The present invention discloses a comprehensive dynamic management scheme of HS-DSCH channel codes, which comprises the steps of: determining a remainder HS-DSCH channel resource of a system when a new HS-DSCH bearer service request is received; calculating a required HS-DSCH channel resource for the new service request; comparing the current system remainder HS-DSCH channel resource with the required HS-DSCH channel resource for the new service request; determining whether there is a need to add new HS-DSCH channel codes based on comparison results, assigning new codes or switching the service request into DCH channel for data transmission in accordance with the actual usage of the current code tree; when the existing HS-DSCH bearer service is completed, calculating a current system HS-DSCH channel resource usage ratio and hysteresis then comparing it with a predefined threshold, and determining whether there is a need to withdraw channel codes based on the results of comparison. The dynamic resource management scheme according to the present invention is well suited for application to future HSDPA technology as the technology is broadly spreading by radio resource management algorithms of radio network controller.

摘要翻译： 本发明公开了一种HS-DSCH信道码综合动态管理方案，包括以下步骤：当收到新的HS-DSCH承载业务请求时，确定系统的余数HS-DSCH信道资源; 为新的服务请求计算所需的HS-DSCH信道资源; 将当前系统余数HS-DSCH信道资源与新服务请求所需的HS-DSCH信道资源进行比较; 基于比较结果确定是否需要添加新的HS-DSCH信道码，根据当前码树的实际使用情况分配新的码或将业务请求切换到DCH信道用于数据传输; 当现有HS-DSCH承载服务完成时，计算当前系统HS-DSCH信道资源使用率和迟滞，然后将其与预定义的阈值进行比较，并且基于比较结果确定是否需要撤销信道码。 根据本发明的动态资源管理方案，由于无线电网络控制器的无线电资源管理算法广泛地扩展了该技术，因此非常适用于将来的HSDPA技术。

公开(公告)号：US20100121806A1

公开(公告)日：2010-05-13

申请号：US12490904

申请日：2009-06-24

申请人： Yi-Zhang Li ,  Zhen-Hua Wang ,  Yuan-Yu Chen ,  Xin Xu ,  Chao Su

发明人： Yi-Zhang Li ,  Zhen-Hua Wang ,  Yuan-Yu Chen ,  Xin Xu ,  Chao Su

IPC分类号： G06F17/50 ,  G06F17/00

CPC分类号： G06F17/50 ,  G06F2217/02

摘要： The present invention relates to an engineering design method and a system of implementing same. In one embodiment, the method includes a construction process of knowledge components and a design process based on the knowledge components. The knowledge components pack universal modules in the standard forms. Accordingly, the knowledge components are independent from design layouts or design processes of products, and reusable in different projects and platforms. The design process integrates a variety of software platforms via a uniform environment and calls the knowledge components to complete the engineering designs. Further, the design process defines a data relation and an execution relation of the knowledge components and establishes a relationship between the knowledge components without programming. The universal module comprises at least operations, methods, rules and/or flows of an engineering design process and engineering analysis process.

摘要翻译： 本发明涉及一种工程设计方法及其实现方法。 在一个实施例中，该方法包括基于知识组件的知识组件的构造过程和设计过程。 知识组件以标准形式包装通用模块。 因此，知识组件独立于产品的设计布局或设计过程，并可在不同的项目和平台中重用。 设计过程通过统一的环境集成了各种软件平台，并调用知识组件来完成工程设计。 此外，设计过程定义知识组件的数据关系和执行关系，并且在没有编程的情况下建立知识组件之间的关系。 通用模块至少包括工程设计过程和工程分析过程的操作，方法，规则和/或流程。

公开(公告)号：US07583702B2

公开(公告)日：2009-09-01

申请号：US11295597

申请日：2005-12-07

申请人： Zongchuang Liang ,  Hua Chao ,  Xin Xu ,  Luoning Gui

发明人： Zongchuang Liang ,  Hua Chao ,  Xin Xu ,  Luoning Gui

IPC分类号： H04J1/00

CPC分类号： H04L27/3411 ,  H04B1/7077 ,  H04B1/7093 ,  H04B2201/70706 ,  H04L5/12

摘要： The present invention discloses a method of transmitting a first signal and a second signal in a wideband code-division multiple access network, wherein a probability of the appearance of signal bit “1” or “0” in each signal of the first signal and the second signal is remarkably higher than a probability of the appearance of “0” or “1”, the method including: a step of determining constellation points, for determining combinations of different states of the first signal and the second signal and for determining each combination as a constellation point; a step of determining locations of constellation points, for determining a location of each constellation point on I-Q plane based on a priori knowledge of said combination; and a step of transmission, for, after modulating said different combinations in different ways according to the location of each constellation point, transporting them to a user equipment via a physical channel. Through joint modulation on the paging indicator and the notification indicator, the transmission method according to the present invention significantly reduces power consumption.

摘要翻译： 本发明公开了一种在宽带码分多址网络中发送第一信号和第二信号的方法，其中在第一信号的每个信号中出现信号比特“1”或“0”的概率， 第二信号明显高于出现“0”或“1”的概率，该方法包括：确定星座点的步骤，用于确定第一信号和第二信号的不同状态的组合，并且用于确定每个组合 作为星座点; 确定星座点的位置的步骤，用于基于所述组合的先验知识来确定I-Q平面上的每个星座点的位置; 以及传输步骤，用于根据每个星座点的位置以不同的方式调制所述不同的组合之后，经由物理信道将它们传送到用户设备。 通过对寻呼指示符和通知指示符的联合调制，根据本发明的传输方法显着地降低了功耗。