-
1.
公开(公告)号:US20120014975A1
公开(公告)日:2012-01-19
申请号:US13182560
申请日:2011-07-14
申请人: Martin Hegen , Stephane Hubert Olland , Yulia Vugmeyster , Xin Xu
发明人: Martin Hegen , Stephane Hubert Olland , Yulia Vugmeyster , Xin Xu
IPC分类号: A61K47/48 , G01N33/53 , A61B19/00 , A61P29/00 , A61P37/06 , G01N33/566 , C07K17/08 , A61K49/00
CPC分类号: C07K16/241 , A61K47/60 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/40 , C07K2317/569 , C07K2317/76 , C07K2317/90 , C07K2317/92
摘要: The invention relates to modified single domain antigen binding molecules, e.g., SDAB molecules, in particular TNFα-binding SDAB molecules. Method of preparing, and using the modified single domain antigen binding molecules described herein, to treat, e.g., TNFα-associated disorders, are also disclosed.
摘要翻译: 本发明涉及修饰的单结构域抗原结合分子,例如SDAB分子,特别是TNFα结合的SDAB分子。 还公开了制备和使用本文所述的修饰的单结构域抗原结合分子来治疗例如TNFα相关疾病的方法。
-
公开(公告)号:US07811567B2
公开(公告)日:2010-10-12
申请号:US11707986
申请日:2007-02-20
IPC分类号: A61K39/395 , C07K16/24
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , Y10S514/861
摘要: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22) and methods of using those antibodies, for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
-
公开(公告)号:US07846444B2
公开(公告)日:2010-12-07
申请号:US12474479
申请日:2009-05-29
IPC分类号: A61K39/395 , C07K16/24
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , Y10S514/861
摘要: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22) and methods of using those antibodies, for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译: 本申请提供了特异性结合人白细胞介素-22(IL-22)的人抗体及其抗原结合片段,以及使用这些抗体的方法,例如诊断,治疗或预防炎性疾病,自身免疫疾病,过敏症,败血症 休克,感染性疾病,移植排斥,癌症和其他免疫系统疾病。
-
公开(公告)号:US20100015162A1
公开(公告)日:2010-01-21
申请号:US12474479
申请日:2009-05-29
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , Y10S514/861
摘要: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22) and methods of using those antibodies, for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译: 本申请提供了特异性结合人白细胞介素-22(IL-22)的人抗体及其抗原结合片段,以及使用这些抗体的方法,例如诊断,治疗或预防炎性疾病,自身免疫疾病,过敏症,败血症 休克,感染性疾病,移植排斥,癌症和其他免疫系统疾病。
-
公开(公告)号:USD400184S
公开(公告)日:1998-10-27
申请号:US64233
申请日:1996-12-24
申请人: Hermann Meiller , Martin Hegen , Raymond Carter
设计人: Hermann Meiller , Martin Hegen , Raymond Carter
-
公开(公告)号:US08906375B2
公开(公告)日:2014-12-09
申请号:US12951734
申请日:2010-11-22
IPC分类号: A61K39/395 , A61P37/06 , A61P37/08 , C07K16/24 , A61K39/00
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , Y10S514/861
摘要: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22) and methods of using those antibodies, for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译: 本申请提供了特异性结合人白细胞介素-22(IL-22)的人抗体及其抗原结合片段,以及使用这些抗体的方法,例如诊断,治疗或预防炎性疾病,自身免疫疾病,过敏症,败血症 休克,感染性疾病,移植排斥,癌症和其他免疫系统疾病。
-
公开(公告)号:US20110091478A1
公开(公告)日:2011-04-21
申请号:US12951734
申请日:2010-11-22
IPC分类号: A61K39/395 , A61P37/06 , A61P37/08
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , Y10S514/861
摘要: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22) and methods of using those antibodies, for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译: 本申请提供了特异性结合人白细胞介素-22(IL-22)的人抗体及其抗原结合片段,以及使用这些抗体的方法,例如诊断,治疗或预防炎性疾病,自身免疫疾病,过敏症,败血症 休克,感染性疾病,移植排斥,癌症和其他免疫系统疾病。
-
公开(公告)号:US20070258982A1
公开(公告)日:2007-11-08
申请号:US11707986
申请日:2007-02-20
IPC分类号: A61K39/395 , A61P1/00 , A61P1/18 , A61P17/00 , A61P17/06 , A61P19/02 , A61P25/00 , A61P31/18 , A61P43/00
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , Y10S514/861
摘要: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22) and methods of using those antibodies, for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译: 本申请提供了特异性结合人白细胞介素-22(IL-22)的人抗体及其抗原结合片段,以及使用这些抗体的方法,例如诊断,治疗或预防炎性疾病,自身免疫疾病,过敏症,败血症 休克,感染性疾病,移植排斥,癌症和其他免疫系统疾病。
-
-
-
-
-
-
-