发明申请
- 专利标题： PYRIMIDINE DERIVATIVES USED AS ITK INHIBITORS
- 专利标题（中）： 用作ITK抑制剂的吡咯烷酮衍生物
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申请号： US13257098申请日： 2010-03-15
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公开(公告)号： US20120058984A1公开(公告)日： 2012-03-08
- 发明人: Catherine Mary Alder , Ian Robert Baldwin , Nicholas Paul Barton , Amanda Jennifer Campbell , Aurelie Cecile Champigny , John David Harling , Aoife Caitriona Maxwell , Juliet Kay Simpson , Ian Edward David Smith , Christopher John Tame , Caroline Wilson , James Michael Woolven
- 申请人： Catherine Mary Alder , Ian Robert Baldwin , Nicholas Paul Barton , Amanda Jennifer Campbell , Aurelie Cecile Champigny , John David Harling , Aoife Caitriona Maxwell , Juliet Kay Simpson , Ian Edward David Smith , Christopher John Tame , Caroline Wilson , James Michael Woolven
- 国际申请： PCT/EP10/53289 WO 20100315
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D417/14 ; A61K31/5377 ; A61K31/541 ; A61P11/00 ; A61P37/08 ; A61P37/00 ; A61P37/06 ; A61P29/00 ; A61P31/18 ; A61P7/06 ; A61P25/00 ; A61P11/06 ; A61P11/08 ; A61P17/00 ; A61P17/06 ; A61P3/10 ; A61P5/16 ; A61P27/02 ; A61P1/00 ; C07D417/12
摘要：
The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular Itk activity.
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