专利检索 ap:"Juliet Kay Simpson" 第 1 页

1.

发明申请
PYRIMIDINE DERIVATIVES USED AS ITK INHIBITORS 审中-公开
标题翻译：用作ITK抑制剂的吡咯烷酮衍生物

公开(公告)号：US20120058984A1

公开(公告)日：2012-03-08

申请号：US13257098

申请日：2010-03-15

申请人： Catherine Mary Alder , Ian Robert Baldwin , Nicholas Paul Barton , Amanda Jennifer Campbell , Aurelie Cecile Champigny , John David Harling , Aoife Caitriona Maxwell , Juliet Kay Simpson , Ian Edward David Smith , Christopher John Tame , Caroline Wilson , James Michael Woolven

发明人： Catherine Mary Alder , Ian Robert Baldwin , Nicholas Paul Barton , Amanda Jennifer Campbell , Aurelie Cecile Champigny , John David Harling , Aoife Caitriona Maxwell , Juliet Kay Simpson , Ian Edward David Smith , Christopher John Tame , Caroline Wilson , James Michael Woolven

IPC分类号： A61K31/506 , C07D417/14 , A61K31/5377 , A61K31/541 , A61P11/00 , A61P37/08 , A61P37/00 , A61P37/06 , A61P29/00 , A61P31/18 , A61P7/06 , A61P25/00 , A61P11/06 , A61P11/08 , A61P17/00 , A61P17/06 , A61P3/10 , A61P5/16 , A61P27/02 , A61P1/00 , C07D417/12

CPC分类号： C07D513/04 , C07D417/12 , C07D417/14

摘要： The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular Itk activity.

摘要翻译： 本发明涉及某些新化合物。具体地，本发明涉及式（I）的化合物及其盐。本发明的化合物是激酶活性的抑制剂，特别是Itk活性。

2.

发明申请
2-Substituted 5-Membered Heteroaryl Carboxylates as Hm74a Receptor Agonists 审中-公开
标题翻译： 2-取代的5元杂芳基羧酸盐作为Hm74a受体激动剂

公开(公告)号：US20080200468A1

公开(公告)日：2008-08-21

申请号：US11815389

申请日：2006-02-14

申请人： Juliet Kay Simpson , Ivan Leo Pinto

发明人： Juliet Kay Simpson , Ivan Leo Pinto

IPC分类号： A61K31/53 , C07D333/36 , C07D401/14 , A61P3/06 , A61P3/00 , A61K31/381

CPC分类号： C07D333/40 , C07D307/68 , C07D409/12

摘要： Therapeutically active heteroaryl carboxylic acid derivatives of Formula (I) wherein R1, R2, W, X, Y and Z are as defined in the specification, processes for the preparation of said derivatives, pharmaceutical formulations containing the active compounds and the use of the compounds in therapy, particularly in the treatment of diseases in which under-activation of the HM74A receptor contributes to the disease or in which activation of the receptor will be beneficial, are disclosed.

摘要翻译： 其中R 1，R 2，W，X，Y和Z的式（I）的治疗活性的杂芳基羧酸衍生物如说明书中所定义，制备方法的所述衍生物，含有活性化合物的药物制剂以及该药物在治疗中的用途，特别是用于治疗其中HM74A受体的未激活有助于该疾病或受体活化将有益的疾病。披露

3.

发明授权
Compounds 有权
标题翻译：化合物

公开(公告)号：US08765743B2

公开(公告)日：2014-07-01

申请号：US12994253

申请日：2009-06-03

申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst

发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst

IPC分类号： A61K31/4439 , A61K31/5377 , A61K31/4545 , A61K31/496 , C07D401/14 , C07D413/14 , C07D405/14 , C07D471/04

CPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D471/04

摘要： The invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

摘要翻译： 本发明涉及式（I）的化合物及其盐。本发明的化合物是PI3-激酶活性的抑制剂。

4.

发明申请
NOVEL COMPOUNDS 审中-公开
标题翻译：新型化合物

公开(公告)号：US20120238559A1

公开(公告)日：2012-09-20

申请号：US13513048

申请日：2010-12-03

申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst

发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst

IPC分类号： A61K31/4439 , A61P37/08 , A61P37/06 , A61P29/00 , A61P9/00 , A61P25/28 , A61P13/12 , A61P7/02 , A61P35/00 , A61P15/00 , A61P9/10 , A61P19/02 , A61P11/06 , C07D401/14 , C07D471/04 , A61K31/437 , C07D413/14 , A61K31/422 , C07D403/14 , A61K31/416 , C07D417/14 , A61K31/427 , C07D491/048 , A61K31/4355 , A61K31/5377 , A61K31/541 , A61K31/4545 , A61P11/00

CPC分类号： C07D401/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D491/048

摘要： The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

摘要翻译： 本发明涉及某些新化合物。具体地，本发明涉及式（I）的化合物及其盐。本发明的化合物是PI3-激酶活性的抑制剂。

5.

发明申请
BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES 有权
标题翻译：作为PI3 KINASES的抑制剂的苯并噻唑衍生物

公开(公告)号：US20110178063A1

公开(公告)日：2011-07-21

申请号：US12994250

申请日：2009-06-03

申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst

发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst

IPC分类号： A61K31/553 , C07D413/14 , A61K31/5377 , C07D417/14 , A61K31/541 , A61K31/5386 , C07D401/14 , A61K31/454 , A61K31/427 , A61K31/496 , A61K31/4439 , C07D471/04 , A61K31/4985 , C07D487/04 , A61K31/519 , A61P11/00 , A61P37/08 , A61P9/00 , A61P19/02 , A61P25/28 , A61P1/00 , A61P7/02 , A61P29/00

CPC分类号： C07D231/56

摘要： The invention is directed to certain novel compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

摘要翻译： 本发明涉及某些新的式（I）化合物及其盐。本发明的化合物是PI3-激酶活性的抑制剂。

6.

发明授权
Benzpyrazol derivatives as inhibitors of PI3 kinases 有权
标题翻译：苯并吡唑衍生物作为PI3激酶的抑制剂

公开(公告)号：US08658635B2

公开(公告)日：2014-02-25

申请号：US12994250

申请日：2009-06-03

申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst

发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst

IPC分类号： A61K31/55 , A61K31/5377 , A61K31/501 , A61K31/496 , A61K31/497 , A61K31/50 , A61K31/505 , A61K31/4523 , A61K31/4427 , A61K31/427 , A61K31/425 , C07D267/02 , C07D279/12 , C07D295/00 , C07D265/30 , C07D413/14 , C07D487/12 , C07D417/12 , C07D211/00 , C07D277/20 , C07D235/00 , C07D233/54 , C07D403/14

CPC分类号： C07D231/56

摘要： The invention is directed to certain novel compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

摘要翻译： 本发明涉及某些新的式（I）化合物及其盐。本发明的化合物是PI3-激酶活性的抑制剂。

7.

发明授权
Compounds 有权
标题翻译：化合物

公开(公告)号：US08536169B2

公开(公告)日：2013-09-17

申请号：US12994254

申请日：2009-06-03

申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Joelle Le , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst

发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Joelle Le , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst

IPC分类号： A61K31/5377 , A61K31/416 , A61K31/454 , A61K31/4439 , C07D401/14 , C07D403/04 , C07D413/14

CPC分类号： C07D403/04 , C07D401/14 , C07D403/14 , C07D413/14 , C07D471/04

摘要： The invention is directed to certain novel compounds directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

摘要翻译： 本发明涉及针对式（I）化合物及其盐的某些新化合物。本发明的化合物是PI3-激酶活性的抑制剂。