Invention Application
- Patent Title: Compositions Comprising Amphotericin B
- Patent Title (中): 包含两性霉素B的组合物
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Application No.: US12087142Application Date: 2006-12-21
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Publication No.: US20120128728A1Publication Date: 2012-05-24
- Inventor: Richard J. Malcolmson , Theresa D. Sweeney , Danforth P. Miller , Alan R. Kugler , Keith Washco , David Han , Ramakrishna Gadiraju , Farzaneh Nakhjiri
- Applicant: Richard J. Malcolmson , Theresa D. Sweeney , Danforth P. Miller , Alan R. Kugler , Keith Washco , David Han , Ramakrishna Gadiraju , Farzaneh Nakhjiri
- Applicant Address: CH Basel
- Assignee: NOVARTIS PHARMA AG
- Current Assignee: NOVARTIS PHARMA AG
- Current Assignee Address: CH Basel
- International Application: PCT/US2006/049119 WO 20061221
- Main IPC: A61K9/14
- IPC: A61K9/14 ; B32B5/16 ; A61P31/10 ; A61K31/7048 ; C07H17/08

Abstract:
The present invention comprises compositions and formulations comprising amphotericin B comprising less than 10% degradants, compositions and formulations comprising amphotericin B with one or more excipients, methods of making amphotericin B compositions and formulations, as well as systems for using amphotericin B compositions and formulations. Also provided are pharmaceutical compositions comprising the formulation, methods of administering the pharmaceutical compositions and methods of treating patients with the pharmaceutical compositions.
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