发明申请
- 专利标题： PHENYL SULPHONAMIDES AS MODULATORS OF ION CHANNELS
- 专利标题（中）： 作为离子通道调节剂的苯乙烯磺酸盐
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申请号： US13419936申请日： 2012-03-14
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公开(公告)号： US20120178713A1公开(公告)日： 2012-07-12
- 发明人: Esther Martinborough , Lev T.D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson
- 申请人： Esther Martinborough , Lev T.D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson
- 申请人地址： US MA Cambridge
- 专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D403/12 ; A61K31/506 ; C07D417/14 ; A61K31/501 ; A61K31/454 ; C07D471/04 ; A61K31/437 ; A61K31/427 ; C07F7/02 ; A61K31/695 ; C07D413/14 ; A61K31/5377 ; A61P35/00 ; A61P19/02 ; A61P25/06 ; A61P25/08 ; A61P25/28 ; A61P25/22 ; A61P25/24 ; A61P1/00 ; A61P13/02 ; C07D417/12
摘要：
The present invention relates to phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.