发明申请
- 专利标题： ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE
- 专利标题（中）： 羟色胺酮激素抑制剂3-激酶
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申请号： US13349868申请日： 2012-01-13
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公开(公告)号： US20120202784A1公开(公告)日： 2012-08-09
- 发明人: Alex Aronov , Jon H. Come , Robert J. Davies , Albert Charles Pierce , Philip N. Collier , Ronald Lee Grey, JR. , Hardwin O'Dowd , James A. Henderson , Elaine B. Krueger , Arnaud Le Tiran , Yusheng Liao , David Messersmith , Jian Wang , Suganthini S. Nanthakumar , Jingrong Cao , Upul Keerthi Bandarage , Anne-Laure Grillot
- 申请人： Alex Aronov , Jon H. Come , Robert J. Davies , Albert Charles Pierce , Philip N. Collier , Ronald Lee Grey, JR. , Hardwin O'Dowd , James A. Henderson , Elaine B. Krueger , Arnaud Le Tiran , Yusheng Liao , David Messersmith , Jian Wang , Suganthini S. Nanthakumar , Jingrong Cao , Upul Keerthi Bandarage , Anne-Laure Grillot
- 申请人地址： US MA Cambridge
- 专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61K31/5377 ; C12N9/99 ; A61K31/496 ; A61K31/551 ; C07D471/20 ; C07D471/04 ; C07D491/20
摘要：
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
公开/授权文献
- US08466288B2 Isoindolinone inhibitors of phosphatidylinositol 3-kinase 公开/授权日：2013-06-18