摘要:
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
摘要:
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
摘要:
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
摘要:
Compounds represented by formula I: or pharmaceutically acceptable salts and solvates thereof, wherein A, B, B′, X, Y, R1, R1′, R2, R2′, R3, R3′, R5, R5′, R6, m, n, or p are as defined herein, are useful for treating flaviviridae viral infections.
摘要:
Compounds represented by formula I: or pharmaceutically acceptable salts and solvates thereof, wherein A, B, B′, X, Y, R1, R1′, R2, R2′, R3, R3′, R5, R5′, R6, m, n, or p are as defined herein, are useful for treating flaviviridae viral infections.
摘要:
A brush seal includes a retainer and a multiplicity of single bristles each bristle having a fixed end and a free sealing end, the fixed ends being individually attached in a continuous arrangement at the same angle to the retainer, the bristles having a uniform pack density throughout the extent of the bristles from the fixed to the sealing end.
摘要:
Contact insertion and wire lay apparatus for manufacture of wire harnesses which provides for insertion of a contact affixed to the trailing end of a wire segment after wire lay. The invention provides for gripping a wire segment while the segment is caused to lay in a desired configuration. A pair of sets of tip jaws enable forward and trailing end contacts of the wire segment to be inserted into selected contact holding devices. In addition, the apparatus is arranged to facilitate lateral receipt and rejection of the wire segments.
摘要:
A battery charger and electronic device assembly is provided for recharging stackable electronic devices in multiple orientation or rotation with respect to each other without the need for either removing batteries or plugging devices into charging racks. In one embodiment of the present invention, a battery charger and rechargeable electronic device assembly includes multiple rechargeable electronic devices with opposing stackable surfaces having a plurality of electrical terminals extending therethrough to place each electronic device in electrical communication with each other device and the battery charger base unit without regard to the orientation the terminals or rotation of the device.
摘要:
A payguide mounting bracket assembly is connected to a support stand, and a spool is connected to the payguide mounting bracket assembly to have a fiber optic coil formed thereon. A pair of payguide assemblies are demountably coupled to the payguide mounting bracket assembly. A robotic manipulator assembly is configured to decouple a selected one of the first and second payguide assemblies from the payguide mounting bracket assembly and move the selected payguide assembly to a location adjacent the spool such that a layer of optical fiber is paid out to the spool from the selected payguide assembly as the spool and payguide mounting bracket assembly rotate relative to the selected payguide assembly. The invention also preferably comprises further comprises an epoxy applicator assembly configured to be demountably coupled to the robotic manipulator assembly for movement to a location adjacent the coil for applying epoxy to the coil.