专利检索 ap:"Philip N. Collier" 第 1 页

1.

发明授权
Isoindolinone inhibitors of phosphatidylinositol 3-kinase 有权
标题翻译：磷脂酰肌醇3-激酶的异吲哚啉酮抑制剂

公开(公告)号：US08466288B2

公开(公告)日：2013-06-18

申请号：US13349868

申请日：2012-01-13

申请人： Alex Aronov , Jon H. Come , Robert J. Davies , Albert Charles Pierce , Philip N. Collier , Ronald Lee Grey, Jr. , Hardwin O'Dowd , James A. Henderson , Elaine B. Krueger , Arnaud Le Tiran , Yusheng Liao , David Messersmith , Jian Wang , Suganthini S. Nanthakumar , Jingrong Cao , Upul Keerthi Bandarage , Anne-Laure Grillot

发明人： Alex Aronov , Jon H. Come , Robert J. Davies , Albert Charles Pierce , Philip N. Collier , Ronald Lee Grey, Jr. , Hardwin O'Dowd , James A. Henderson , Elaine B. Krueger , Arnaud Le Tiran , Yusheng Liao , David Messersmith , Jian Wang , Suganthini S. Nanthakumar , Jingrong Cao , Upul Keerthi Bandarage , Anne-Laure Grillot

IPC分类号： C07D471/02 , C07D213/04 , C07D401/00 , C07D401/02 , C12N9/99 , A61K31/437

CPC分类号： C07D409/14 , C07D401/04 , C07D401/14 , C07D405/14 , C07D417/14 , C07D471/04 , C07D471/20 , C07D491/20

摘要： The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

摘要翻译： 本发明涉及可用作PI3K抑制剂，特别是PI3Kgamma的化合物。本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病，病症或病症的方法。

2.

发明授权
Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases 失效
标题翻译：可用作蛋白激酶抑制剂的氨基吡啶和氨基嘧啶

公开(公告)号：US08372850B2

公开(公告)日：2013-02-12

申请号：US12433998

申请日：2009-05-01

申请人： Juan Miguel Jimenez , Philip N. Collier , Andrew Miller

发明人： Juan Miguel Jimenez , Philip N. Collier , Andrew Miller

IPC分类号： C07D403/12 , A61K31/506

CPC分类号： C07D403/12 , C07D403/14 , C07D417/12 , C07D417/14 , C07D471/04

摘要： The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

摘要翻译： 本发明涉及可用作蛋白激酶抑制剂的化合物。本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病，病症或病症的方法。本发明还提供了制备本发明化合物的方法。

3.

发明申请
ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE 审中-公开

公开(公告)号：US20120040950A1

公开(公告)日：2012-02-16

申请号：US12974388

申请日：2010-12-21

申请人： Alex Aronov , Jon H. Come , Robert J. Davies , Albert Charles Pierce , Philip N. Collier , Ronald Lee Grey, JR. , Hardwin O'Dowd , James A. Henderson , Elaine B. Krueger , Arnaud Le Tiran , Yusheng Liao , David Messersmith , Jian Wang , Suganthini S. Nanthakumar , Jingrong Cao , Upul Keerthi Bandarage , Anne-Laure Grillot

发明人： Alex Aronov , Jon H. Come , Robert J. Davies , Albert Charles Pierce , Philip N. Collier , Ronald Lee Grey, JR. , Hardwin O'Dowd , James A. Henderson , Elaine B. Krueger , Arnaud Le Tiran , Yusheng Liao , David Messersmith , Jian Wang , Suganthini S. Nanthakumar , Jingrong Cao , Upul Keerthi Bandarage , Anne-Laure Grillot

IPC分类号： A61K31/4439 , C07D401/14 , A61K31/444 , C07D471/04 , A61K31/437 , C07D403/14 , A61K31/506 , C07D413/14 , A61K31/5377 , A61P37/00 , A61P29/00 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P25/14 , C12N9/99 , C07D401/10

CPC分类号： C07D409/14 , C07D401/04 , C07D401/14 , C07D405/14 , C07D417/14 , C07D471/04 , C07D471/20 , C07D491/20

摘要： The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

4.

发明授权
Tri-cyclic pyrazolopyridine kinase inhibitors 有权
标题翻译：三环吡唑并吡啶激酶抑制剂

公开(公告)号：US08569337B2

公开(公告)日：2013-10-29

申请号：US12670989

申请日：2010-01-27

申请人： Juan-Miguel Jimenez , John Studley , Ronald Knegtel , Luca Settimo , Christopher John Davis , Damien Fraysse , Philip N. Collier , Guy Brenchley , Dean Boyall , Andrew Miller , Heather Twin , Stephen Young

发明人： Juan-Miguel Jimenez , John Studley , Ronald Knegtel , Luca Settimo , Christopher John Davis , Damien Fraysse , Philip N. Collier , Guy Brenchley , Dean Boyall , Andrew Miller , Heather Twin , Stephen Young

IPC分类号： A61K31/437 , C07D471/04

CPC分类号： C07D471/04 , A61K31/496 , A61K31/506 , C07D239/24 , C07D241/10 , C07D519/00

摘要： The present invention relates to compounds of tri-cyclic pyrazolopyridine useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions containing such compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

摘要翻译： 本发明涉及可用作蛋白激酶抑制剂的三环吡唑并吡啶化合物。本发明还提供含有这些化合物的药学上可接受的组合物和使用该组合物治疗各种疾病，病症或病症的方法。本发明还提供了制备本发明化合物的方法。

5.

发明申请
PYRAZOLOPYRIDINE KINASE INHIBITORS 审中-公开
标题翻译：吡唑啉激酶抑制剂

公开(公告)号：US20130053395A1

公开(公告)日：2013-02-28

申请号：US13560119

申请日：2012-07-27

申请人： Juan-Miguel Jimenez , Julian M.C. Golec , Luca Settimo , Damien Fraysse , Guy Brenchley , Dean Boyall , Heather Twin , Stephen Young , Andrew W. Miller , Christopher John Davis , Philip N. Collier

发明人： Juan-Miguel Jimenez , Julian M.C. Golec , Luca Settimo , Damien Fraysse , Guy Brenchley , Dean Boyall , Heather Twin , Stephen Young , Andrew W. Miller , Christopher John Davis , Philip N. Collier

IPC分类号： A61K31/496 , A61P37/06 , A61P29/00 , A61P35/00 , A61P11/06 , A61P19/04 , A61P19/02 , A61P25/00 , A61P3/10 , A61P1/00 , A61P35/02 , C07D471/04 , A61P17/06

CPC分类号： C07D471/04

摘要： The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

摘要翻译： 本发明涉及可用作蛋白激酶抑制剂的化合物。本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病，病症或病症的方法。本发明还提供了制备本发明化合物的方法。