发明申请
- 专利标题： THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS
- 专利标题（中）： 用于RNA合成的THIOCARBON保护组
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申请号： US13485592申请日： 2012-05-31
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公开(公告)号： US20120238737A1公开(公告)日： 2012-09-20
- 发明人: Douglas J. Dellinger , Agnieszka Sierzchala , John Turner , Joel Myerson , Zoltan Kupihar , Fernando Ferreira , Marvin H. Caruthers , Geraldine F. Dellinger
- 申请人： Douglas J. Dellinger , Agnieszka Sierzchala , John Turner , Joel Myerson , Zoltan Kupihar , Fernando Ferreira , Marvin H. Caruthers , Geraldine F. Dellinger
- 申请人地址： US CA Santa Clara
- 专利权人： Agilent Technologies, Inc.
- 当前专利权人： Agilent Technologies, Inc.
- 当前专利权人地址： US CA Santa Clara
- 主分类号： C07H1/00
- IPC分类号： C07H1/00 ; C07H19/20 ; C07H21/02 ; C07H19/10
摘要：
Aspects of the invention include 2′ protected nucleoside monomers that are protected at the 2′ site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.
公开/授权文献
- US09067961B2 Thiocarbon-protecting groups for RNA synthesis 公开/授权日：2015-06-30
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