发明申请
US20120302496A1 NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES
审中-公开
来自真菌菌株的新型24位CYCLOOCTADEPSIPEPTISES及其作为安非他明或内给药的用途
- 专利标题： NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES
- 专利标题（中）： 来自真菌菌株的新型24位CYCLOOCTADEPSIPEPTISES及其作为安非他明或内给药的用途
-
申请号： US13514538申请日： 2010-12-07
-
公开(公告)号： US20120302496A1公开(公告)日： 2012-11-29
- 发明人: Achim Harder , Klemens Krieger , Thi Lam Huong Pham , Thanh Dam Huynh , Irmtraut Zaspel , Dietrich Ewald , Clemens Mügge , Hardy Weisshoff
- 申请人： Achim Harder , Klemens Krieger , Thi Lam Huong Pham , Thanh Dam Huynh , Irmtraut Zaspel , Dietrich Ewald , Clemens Mügge , Hardy Weisshoff
- 申请人地址： DE MONHEIM
- 专利权人： BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人： BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人地址： DE MONHEIM
- 优先权： EP0978799.4 20091211
- 国际申请： PCT/EP2010/069040 WO 20101207
- 主分类号： C07K11/02
- IPC分类号： C07K11/02 ; A61P33/10 ; A61P33/00 ; C12P21/04 ; A61K38/15
摘要：
The present invention relates firstly to the discovery of the previously unknown 24-membered cyclooctadepsipeptides PF1022-V, PF1022-W, XRB-C894, XRB-C942, XRB-C976, XRB-C1010, XRB-C1044, XRB-E922, XRB-E956, XRB-E990, XRB-E1024, XRB-S958, XRB-S992, XRB-S1026, XRB-S1060 (in various isomeric forms) and to the processes for the preparation of the abovementioned cyclooctadepsipeptides by means of the fungal strains from the family Xylariaceae, in particular the genera Rosellinia and Coniolariella, and by means of the mitosporic fungal strains from the groups Fusarium, Beauveria and Verticillium (orders Hypocreales and Phyllachorales), and by means of the enzymatic preparations isolated from these fungal strains, and secondly to the use of these strains for the preparation of the abovementioned novel cyclooctadepsipeptides and to the use of bassianolide and of the abovementioned novel cyclooctadepsipeptides individually or as a mixture, as anthelmintics or endoparasiticides.
信息查询
