Invention Application
US20130149733A1 ESTABLISHMENT OF RHESUS MONKEY MODEL OF AUTOIMMUNITY TYPE 1 DIABETES
有权
建立自动免疫型1型糖尿病的神经元模型
- Patent Title: ESTABLISHMENT OF RHESUS MONKEY MODEL OF AUTOIMMUNITY TYPE 1 DIABETES
- Patent Title (中): 建立自动免疫型1型糖尿病的神经元模型
-
Application No.: US13637125Application Date: 2010-03-26
-
Publication No.: US20130149733A1Publication Date: 2013-06-13
- Inventor: Yanrong Lu , Jingqiu Cheng , Shaoping Deng , Younan Chen , Bole Tian , Gang Mai , Yan Ren , Li Wang , Hongxia Li , Lingling Wei , Xi Jin , Chaofeng Qiao , Wensheng Zhang , Sirong He , Li Zeng
- Applicant: Yanrong Lu , Jingqiu Cheng , Shaoping Deng , Younan Chen , Bole Tian , Gang Mai , Yan Ren , Li Wang , Hongxia Li , Lingling Wei , Xi Jin , Chaofeng Qiao , Wensheng Zhang , Sirong He , Li Zeng
- Applicant Address: CN Sichuan
- Assignee: West China Hospital, Sichuan University
- Current Assignee: West China Hospital, Sichuan University
- Current Assignee Address: CN Sichuan
- International Application: PCT/CN2010/000378 WO 20100326
- Main IPC: A01K67/027
- IPC: A01K67/027 ; C12Q1/02
Abstract:
Use of low dose streptozocin in the preparation of an animal model for screening drugs for treatment of antoimmune type 1 diabetes is disclosed, in which streptozocin is administrated intravenously at a dose of 15-30 mg/kg per time for 5 days and administrated again on the 7th day and 14th day after last time of offering drug. A method for preparing rhesus monkey model of autoimmune type 1 diabetes and autoimmune type 1 diabetes animal model obtained are also disclosed.
Public/Granted literature
- US09186421B2 Establishment of rhesus monkey model of autoimmunity type 1 diabetes Public/Granted day:2015-11-17
Information query
