发明申请
US20140287427A1 COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS
审中-公开
用于捕获生物活性剂细胞目标的组合物和方法
- 专利标题： COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS
- 专利标题（中）： 用于捕获生物活性剂细胞目标的组合物和方法
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申请号： US14204868申请日： 2014-03-11
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公开(公告)号： US20140287427A1公开(公告)日： 2014-09-25
- 发明人: Carolyn W. Hitko , Robin Hurst , Thomas Kirkland , Dieter Klaubert , Poncho Meisenheimer , Nidhi Nath , Rachel Friedman Ohana , Paul Otto , Marjeta Urh , Tetsuo Uyeda , Keith Wood
- 申请人： Promega Corporation
- 申请人地址： US WI Madison
- 专利权人： Promega Corporation
- 当前专利权人： Promega Corporation
- 当前专利权人地址： US WI Madison
- 主分类号： G01N33/569
- IPC分类号： G01N33/569
摘要：
The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture dimers), surfaces (e.g., displaying, capture ligands, capture proteins, or capture dimers), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.
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