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公开(公告)号：US20240369459A1
公开(公告)日：2024-11-07
申请号：US18654908
申请日：2024-05-03
Applicant: Promega Corporation
Inventor： Kevin Mayer , Hui Wang , Douglas Horejsh , Marjeta Urh , Wenhui Zhou
IPC: G01N1/30 , C07C211/03 , C07D261/02 , C07D265/02 , C07F9/38 , C12N9/58
Abstract: Provided herein are methods, compositions, and kits for decrosslinking formaldehyde cross-linked biological samples such as formalin-fixed, paraffin-embedded (FFPE) tissue samples.
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公开(公告)号：US10247711B2
公开(公告)日：2019-04-02
申请号：US14180125
申请日：2014-02-13
Applicant: Promega Corporation
Inventor： Joshua Jacques Coon , Michael M. Rosenblatt , Marjeta Urh
Abstract: The present invention provides reagents for instrumentation quality control and methods of use thereof. In particular, sets of peptides or other molecules are provided for evaluating the performance of instruments with mass spectrometry (MS) and/or liquid chromatography (LC) functionalities.
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公开(公告)号：US20180224441A1
公开(公告)日：2018-08-09
申请号：US15892557
申请日：2018-02-09
Applicant: Promega Corporation
Inventor： Nidhi Nath , Rod Flemming , Marjeta Urh
IPC: G01N33/543 , G01N33/94 , C07K16/28 , G01N33/58
CPC classification number: G01N33/54306 , C07K16/2863 , C07K2317/24 , G01N33/58 , G01N33/582 , G01N33/94
Abstract: Provided herein are compositions, kits, and methods for performing analyte detection immunoassays.
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公开(公告)号：US10976312B2
公开(公告)日：2021-04-13
申请号：US15402879
申请日：2017-01-10
Applicant: Promega Corporation
Inventor： Carolyn W. Hitko , Robin Hurst , Thomas Kirkland , Dieter Klaubert , Poncho Meisenheimer , Nidhi Nath , Rachel Friedman Ohana , Paul Otto , Marjeta Urh , Harry Tetsuo Uyeda , Keith Wood , Ji Zhu
IPC: G01N33/543
Abstract: The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture fusions), surfaces (e.g., displaying, capture ligands, capture proteins, or capture fusions), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.
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公开(公告)号：US10168323B2
公开(公告)日：2019-01-01
申请号：US14204868
申请日：2014-03-11
Applicant: Promega Corporation
Inventor： Carolyn W. Hitko , Robin Hurst , Thomas Kirkland , Dieter Klaubert , Poncho Meisenheimer , Nidhi Nath , Rachel Friedman Ohana , Paul Otto , Marjeta Urh , Harry Tetsuo Uyeda , Keith Wood
IPC: G01N33/569 , G01N33/543 , G01N33/50
Abstract: The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture dimers), surfaces (e.g., displaying, capture ligands, capture proteins, or capture dimers), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.
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Patent Agency Ranking
公开(公告)号：US20140230517A1
公开(公告)日：2014-08-21
申请号：US14180125
申请日：2014-02-13
Applicant: Promega Corporation
Inventor： Joshua Jacques Coon , Michael M. Rosenblatt , Marjeta Urh
IPC: G01N30/72
CPC classification number: G01N30/8665 , G01N2030/027 , G01N2030/047 , G01N2030/8831 , H01J49/0009
Abstract: The present invention provides reagents for instrumentation quality control and methods of use thereof. In particular, sets of peptides or other molecules are provided for evaluating the performance of instruments with mass spectrometry (MS) and/or liquid chromatography (LC) functionalities.
Abstract translation: 本发明提供了用于仪器质量控制的试剂及其使用方法。 特别地，提供了肽或其他分子的集合来评估仪器的质谱（MS）和/或液相色谱（LC）功能的性能。
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公开(公告)号：US20240368680A1
公开(公告)日：2024-11-07
申请号：US18654939
申请日：2024-05-03
Applicant: Promega Corporation
Inventor： Hui Wang , Kevin Mayer , Douglas Horejsh , Marjeta Urh , Wenhui Zhou , Michael M. Rosenblatt
IPC: C12Q1/6851 , C12Q1/6806 , G01N1/30
Abstract: Disclosed herein are compositions and methods for decrosslinking formaldehyde cross-linked biological samples such as formalin-fixed, paraffin-embedded (FFPE) tissue samples.
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公开(公告)号：US10900939B2
公开(公告)日：2021-01-26
申请号：US16275417
申请日：2019-02-14
Applicant: Promega Corporation
Inventor： Joshua Jacques Coon , Michael M. Rosenblatt , Marjeta Urh
Abstract: The present invention provides reagents for instrumentation quality control and methods of use thereof. In particular, sets of peptides or other molecules are provided for evaluating the performance of instruments with mass spectrometry (MS) and/or liquid chromatography (LC) functionalities.
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9.发明申请COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS 审中-公开用于捕获生物活性剂细胞目标的组合物和方法公开(公告)号：US20140287427A1
公开(公告)日：2014-09-25
申请号：US14204868
申请日：2014-03-11
Applicant: Promega Corporation
Inventor： Carolyn W. Hitko , Robin Hurst , Thomas Kirkland , Dieter Klaubert , Poncho Meisenheimer , Nidhi Nath , Rachel Friedman Ohana , Paul Otto , Marjeta Urh , Tetsuo Uyeda , Keith Wood
IPC: G01N33/569
CPC classification number: G01N33/543 , G01N33/5005
Abstract: The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture dimers), surfaces (e.g., displaying, capture ligands, capture proteins, or capture dimers), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.
Abstract translation: 本发明提供用于捕获和鉴定生物活性剂的细胞靶标的组合物和方法。 特别地，本文提供的是用于捕获配体，细胞靶标（任选地用报告物标记），捕获蛋白质（任选地作为捕获二聚体存在），表面（例如显示，捕获配体，捕获蛋白质或捕获二聚体）的生物活性剂， 以及捕获和鉴定生物活性剂的细胞靶标的方法。
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公开(公告)号：US11327072B2
公开(公告)日：2022-05-10
申请号：US15892557
申请日：2018-02-09
Applicant: Promega Corporation
Inventor： Nidhi Nath , Rod Flemming , Marjeta Urh
IPC: G01N33/543 , G01N33/94 , C07K16/28 , G01N33/58
Abstract: Provided herein are compositions, kits, and methods for performing analyte detection immunoassays.
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