Invention Application
- Patent Title: IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF
- Patent Title (中): 可离子化合物及其组合物及其用途
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Application No.: US15191511Application Date: 2016-06-23
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Publication No.: US20160376229A1Publication Date: 2016-12-29
- Inventor: Roger Adami , Hao Bai , John Gaudette , Bharat Majeti , Seiji Nukui , Kwok Yin Tsang , Hai Wang , Haiqing Ying , Wenbin Ying
- Applicant: Nitto Denko Corporation
- Main IPC: C07C271/16
- IPC: C07C271/16 ; A61K47/22 ; C07D207/12 ; A61K47/16 ; C07C237/16 ; A61K31/713 ; C07D211/86 ; C07D211/82 ; C07D211/74 ; C07F9/06 ; A61K47/24 ; C07D205/04 ; C07D207/09

Abstract:
This invention includes ionizable compounds, and compositions and methods of use thereof. The ionizable compounds can be used for making nanoparticle compositions for use in biopharmaceuticals and therapeutics. More particularly, this invention relates to compounds, compositions and methods for providing nanoparticles to encapsulate active agents, such as nucleic acid agents, and to deliver and distribute the active agents to cells, tissues, organs, and subjects.
Public/Granted literature
- US10167253B2 Ionizable compounds and compositions and uses thereof Public/Granted day:2019-01-01
Information query