Invention Application
US20170002040A1 NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA 审中-公开
治疗GLAUCOMA的新疗法

NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA
Abstract:
The present invention provides benzothiadiazine and chroman derivatives and particularly diazoxide and cromakalim derivatives for use in treating glaucoma, retinopathy, treating age related macular degeneration, treating, stabilizing and/or inhibiting blood and lymph vascularization, and reducing intraocular pressure by administering a pharmaceutically effective amount of a prodrug disposed in an ophthalmically acceptable carrier to the eye, wherein the prodrug specifically modulates a KATP channel to reduce an intraocular pressure.
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