Invention Application
- Patent Title: NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA
- Patent Title (中): 治疗GLAUCOMA的新疗法
-
Application No.: US15113773Application Date: 2015-01-30
-
Publication No.: US20170002040A1Publication Date: 2017-01-05
- Inventor: Michael P. Fautsch , Peter Dosa , Michael A. Walters , Gunda I. Georg
- Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , REGENTS OF THE UNIVERSITY OF MINNESOTA
- International Application: PCT/US15/13955 WO 20150130
- Main IPC: C07K5/062
- IPC: C07K5/062 ; C07D405/14 ; C07F9/6558 ; C07D285/24 ; C07D311/70 ; C07D311/20 ; C07F9/6547 ; C07D405/04 ; C07D405/12

Abstract:
The present invention provides benzothiadiazine and chroman derivatives and particularly diazoxide and cromakalim derivatives for use in treating glaucoma, retinopathy, treating age related macular degeneration, treating, stabilizing and/or inhibiting blood and lymph vascularization, and reducing intraocular pressure by administering a pharmaceutically effective amount of a prodrug disposed in an ophthalmically acceptable carrier to the eye, wherein the prodrug specifically modulates a KATP channel to reduce an intraocular pressure.
Public/Granted literature
- US10981951B2 Therapeutics for the treatment of glaucoma Public/Granted day:2021-04-20
Information query