Invention Application
US20170058282A1 GENETICALLY ENGINEERED SENSORS FOR IN VIVO DETECTION OF BLEEDING
审中-公开
用于血液检测的遗传工程传感器
- Patent Title: GENETICALLY ENGINEERED SENSORS FOR IN VIVO DETECTION OF BLEEDING
- Patent Title (中): 用于血液检测的遗传工程传感器
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Application No.: US15205625Application Date: 2016-07-08
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Publication No.: US20170058282A1Publication Date: 2017-03-02
- Inventor: Timothy Kuan-Ta Lu , Mark K. Mimee
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Main IPC: C12N15/70
- IPC: C12N15/70 ; C12Q1/02 ; C12Q1/68 ; C12N15/63 ; A61K49/00
Abstract:
Provided herein are microorganisms engineered with heme-responsive transcription factors and genetic circuits. Also provided are methods for using engineered microorganisms to sense bleeding events and treat bleeding in vivo.
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