Invention Application
- Patent Title: LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF
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Application No.: US15369701Application Date: 2016-12-05
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Publication No.: US20170143852A1Publication Date: 2017-05-25
- Inventor: Jinming GAO , Gang HUANG , Tian ZHAO , Xinpeng MA , Yiguang WANG , Yang LI , Baran D. SUMER
- Applicant: The Board of Regents of the University of Texas System
- Main IPC: A61K49/00
- IPC: A61K49/00 ; G01N33/58 ; C08F8/30 ; G01N21/64 ; C08F8/32 ; C08F8/34 ; C09B69/10 ; G01N33/84 ; C08F8/42

Abstract:
The present disclosure relates to polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH. In some aspects, the polymers form a micelle which is sensitive to pH and results in a change in fluorescence based upon the particular pH. In some aspects, the disclosure also provides methods of using the polymers for the imaging of cellular or extracellular environment or delivering a drug.
Public/Granted literature
- US10098971B2 Library of pH responsive polymers and nanoprobes thereof Public/Granted day:2018-10-16
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