Invention Application
- Patent Title: INDANE INHIBITORS OF EED AND METHODS OF THEIR USE
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Application No.: US15588398Application Date: 2017-05-05
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Publication No.: US20170320880A1Publication Date: 2017-11-09
- Inventor: Michael R. Michaelides , Michael L. Curtin , Huan-Qiu Li , Marina A. Pliushchev , Ying Wang , Hongyu H. Zhao , Richard F. Clark , Alan S. Florjancic , Zhiqin Ji , Mariazel Torrent , Ramzi F. Sweis , Anil Vasudevan , Justin D. Dietrich
- Applicant: AbbVie Inc.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D417/14 ; C07D413/10 ; C07D405/04 ; C07D403/14 ; C07D403/12 ; C07D403/10 ; C07D403/04 ; C07D401/14 ; C07D401/12 ; C07D401/04 ; C07D471/04 ; C07D207/14
Abstract:
Compounds having a structure of Formula (I): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein A1, A2, A3, A4, A5, n, and m are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various EED-related conditions or diseases, including cancer, by administration of such compounds are also provided.
Public/Granted literature
- US09957274B2 Indane inhibitors of EED and methods of their use Public/Granted day:2018-05-01
Information query
