Invention Application
- Patent Title: COMPOSITIONS AND METHODS FOR ENHANCING ONCOLYTIC VIRUS EFFICACY
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Application No.: US15542480Application Date: 2016-01-26
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Publication No.: US20180305345A1Publication Date: 2018-10-25
- Inventor: Jean-Simon Diallo , Christopher Noyce Boddy , Mark Dornan , Ramya Krishnan , Fabrice Le Boeuf , John C. Bell , Andrew Macklin , Jeffrey Smith
- Applicant: Ottawa Hospital Research Institute , University of Ottawa
- Applicant Address: CA ON Ottawa CA ON Ottawa
- Assignee: Ottawa Hospital Research Institute,University of Ottawa
- Current Assignee: Ottawa Hospital Research Institute,University of Ottawa
- Current Assignee Address: CA ON Ottawa CA ON Ottawa
- International Application: PCT/CA2016/050062 WO 20160126
- Main IPC: C07D413/06
- IPC: C07D413/06 ; C07D207/38 ; C07D207/456 ; C07D209/48 ; C07D231/08 ; C07D237/14 ; C07D307/58 ; C07D307/60 ; C07D307/66 ; C07D317/64 ; C07D401/06 ; C07D403/06 ; C07D405/04 ; C07D405/12 ; C07D409/06 ; C07D471/04 ; A61P35/02
Abstract:
Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the cytotoxicity of virus to cells. Other uses, compositions and methods of using same are also provided.
Information query
