- 专利标题: METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS
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申请号: US15902690申请日: 2018-02-22
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公开(公告)号: US20180311263A1公开(公告)日: 2018-11-01
- 发明人: Byoung Kwon Chun , Michael O' Neil Hanrahan Clarke , Edward Doerffler , Hon Chung Hui , Robert Jordan , Richard L. Mackman , Jay P. Parrish , Adrian S. Ray , Dustin Siegel
- 申请人: Gilead Sciences, Inc.
- 主分类号: A61K31/685
- IPC分类号: A61K31/685 ; A61K31/53 ; A61K31/00 ; A61K31/6615 ; A61K31/665 ; A61K31/683 ; C07D487/04 ; C07H15/18 ; C07H11/00 ; C07H1/02 ; C07H1/00 ; A61K45/06 ; A61K31/675 ; C07F9/6561 ; C07F9/24 ; C07D519/00
摘要:
Provided are compounds, methods, and pharmaceutical compositions for treating Filoviridae virus infections by administering ribosides, riboside phosphates and prodrugs thereof, of Formula IV: The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.
公开/授权文献
- US10251898B2 Methods for treating Filoviridae virus infections 公开/授权日:2019-04-09
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