发明申请
- 专利标题: Dicarboxylic Acid Foamable Vehicle and Pharmaceutical Compositions Thereof
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申请号: US16189767申请日: 2018-11-13
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公开(公告)号: US20190076356A1公开(公告)日: 2019-03-14
- 发明人: Dov Tamarkin , Doron Friedman , Tal Berman , Enbal Ziv , David Schuz
- 申请人: Foamix Pharmaceuticals Ltd.
- 优先权: IL152486 20021025
- 主分类号: A61K9/12
- IPC分类号: A61K9/12 ; A61K8/362 ; A61K8/37 ; A61K8/49 ; A61K8/86 ; A61K8/04 ; A61Q19/00 ; A01N25/16 ; A61K9/00
摘要:
The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.