Invention Application
- Patent Title: POLY (BETA-AMINO ESTERS) AND USES THEREOF
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Application No.: US16170318Application Date: 2018-10-25
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Publication No.: US20190125874A1Publication Date: 2019-05-02
- Inventor: Daniel Griffith Anderson , Kevin John Kauffman , James C. Kaczmarek , Asha Kumari Patel
- Applicant: Massachusetts Institute of Technology
- Main IPC: A61K47/18
- IPC: A61K47/18 ; A61K47/32 ; A61K47/34 ; C08G63/685 ; A61K9/12
Abstract:
Provided herein are branched poly(beta-amino esters) (PBAE) useful as vehicles for the delivery of therapeutic agents, such as nucleic acids. The disclosed polymers form stable compositions, and are suitable for the delivery of therapeutic agents via nebulization. Compositions of the disclosed polymers are capable of delivering therapeutic agents such as mRNA to lung epithelial cells.
Public/Granted literature
- US11464860B2 Poly (beta-amino esters) and uses thereof Public/Granted day:2022-10-11
Information query
IPC分类:
