- 专利标题： PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII
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申请号： US16389292申请日： 2019-04-19
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公开(公告)号： US20190321440A1公开(公告)日： 2019-10-24
- 发明人: Konrad BLEICHER , Daniella CHEANG , Patrick DI GIORGIO , Taishan HU , Christian JENNY , Patrizio MATTEI , Petra SCHMITZ , Theodor STOLL
- 申请人： Hoffmann-La Roche Inc.
- 申请人地址： US NJ Little Falls
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Little Falls
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; A61P31/04
摘要：
The present invention provides compounds of formula (I) wherein X1, X2, R1 to R6 and A are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by bacteria.
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