- 专利标题： OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEOSIDE LINKAGE
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申请号： US17720676申请日： 2022-04-14
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公开(公告)号： US20230002762A1公开(公告)日： 2023-01-05
- 发明人: Konrad Bleicher , Henrik Frydenlund HANSEN , Troels KOCH , Jesper WORM , Adrian SCHAEUBLIN , Erik FUNDER , Joerg DUSCHMALÉ , Lars JOENSON , Meiling LI , Martina Brigitte DUSCHMALÉ , Yong WU , Xi SHU
- 申请人： ROCHE INNOVATION CENTER COPENHAGEN A/S
- 申请人地址： DK HØRSHOLM
- 专利权人： ROCHE INNOVATION CENTER COPENHAGEN A/S
- 当前专利权人： ROCHE INNOVATION CENTER COPENHAGEN A/S
- 当前专利权人地址： DK HØRSHOLM
- 优先权： CNPCT/CN2017/118040 20171222,EP18198479.0 20181003
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C07H1/00 ; C07H21/00
摘要：
The present invention relates to an oligonucleotide comprising at least one phosphorodithioate internucleoside linkage of formula (I) (I) as defined in the description and in the claim. The oligonucleotide of the invention can be used as a medicement.
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