Invention Publication
- Patent Title: POLYMER MATERIALS
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Application No.: US17947603Application Date: 2022-09-19
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Publication No.: US20230172496A1Publication Date: 2023-06-08
- Inventor: John Kenneth Hicks , Richard Hoskins , Stephen Rimmer , Dorothy McCulloch
- Applicant: Smith & Nephew PLC , University Of Sheffield
- Applicant Address: GB Watford
- Assignee: Smith & Nephew PLC,University Of Sheffield
- Current Assignee: Smith & Nephew PLC,University Of Sheffield
- Current Assignee Address: GB Watford
- Priority: GB 00746.0 2016.01.14
- Main IPC: A61B5/145
- IPC: A61B5/145 ; A61L15/22 ; C08G18/48 ; C08G18/24 ; C08G18/76 ; A61L15/56 ; C08L75/04 ; C08G18/28 ; A61F13/00 ; C08G18/73 ; C08G18/10 ; A61B5/00 ; A61F13/84 ; A61F15/00 ; A61L15/26 ; A61L15/42 ; C08J5/18 ; C08J9/00 ; C08J9/30 ; C09J11/08 ; C09J175/04 ; G01N33/84

Abstract:
Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising:
hydrophilic monomer; and
indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer;
characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10
and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.
hydrophilic monomer; and
indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer;
characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10
and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.
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