- 专利标题: BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
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申请号: US17361758申请日: 2021-06-29
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公开(公告)号: US20230027019A1公开(公告)日: 2023-01-26
- 发明人: Hang Chu , Ana Z. Gonzalez Buenrostro , Hongyan Guo , Xiaochun Han , Lan Jiang , Jiayao Li , Michael L. Mitchell , Hyung-Jung Pyun , Scott D. Schroeder , Gregg M. Schwarzwalder , Nathan D. Shapiro , Devleena M. Shivakumar , Qiaoyin Wu , Hong Yang , Jennifer R. Zhang
- 申请人: Gilead Sciences, Inc.
- 申请人地址: US CA Foster City
- 专利权人: Gilead Sciences, Inc.
- 当前专利权人: Gilead Sciences, Inc.
- 当前专利权人地址: US CA Foster City
- 主分类号: C07D498/18
- IPC分类号: C07D498/18 ; C07D471/18 ; A61P31/18
摘要:
Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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