Invention Publication
- Patent Title: RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME
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Application No.: US18323215Application Date: 2023-05-24
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Publication No.: US20230303669A1Publication Date: 2023-09-28
- Inventor: Kurt SWANSON , Philip R. DORMITZER
- Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
- Applicant Address: BE Rixensart
- Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee Address: BE Rixensart
- Main IPC: C07K16/10
- IPC: C07K16/10 ; A61K39/155 ; A61K39/12 ; C07K14/005

Abstract:
The present invention relates to immunogenic compositions comprising RSV F protein, methods for preparing compositions that contain RSV F protein ecto-domain polypeptides, and to certain engineered RSV F proteins and nucleic acids that encode the engineered RSV F proteins. Compositions prepared using the methods can contain RSV F protein ecto-domain polypeptides in a predominant or single desired form and conformation. The invention also relates to methods for inducing an immune response to RSV F.
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