发明申请
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS](/docs/US/2023-02-09/US20230041738A1/abs.jpg.600x600.jpg)
- 专利标题： 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
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申请号： US17793174申请日： 2021-01-26
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公开(公告)号： US20230041738A1公开(公告)日： 2023-02-09
- 发明人: Yam B. POUDEL , Matthew COX , Liqi HE , Ashvinikumar V. GAVAI , Sanjeev GANGWAR , Mathias BROEKEMA , Christine M. TARBY , Murugaiah ANDAPPAN MURUGAIAH SUBBAIAH
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址： US NJ Princeton
- 专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人地址： US NJ Princeton
- 国际申请： PCT/US2021/014982 WO 20210126
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D519/00 ; C07D487/04 ; A61K31/5386 ; A61K39/395
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS](/abs-image/US/2023/02/09/US20230041738A1/abs.jpg.150x150.jpg)
摘要：
Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). (I) Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.
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