Invention Application
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS](/docs/US/2023-04-20/US20230118688A1/abs.jpg.600x600.jpg)
- Patent Title: 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
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Application No.: US17792869Application Date: 2021-01-26
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Publication No.: US20230118688A1Publication Date: 2023-04-20
- Inventor: Heng CHENG , Christine M. TARBY , Sanjeev GANGWAR , Ashvinikumar V. GAVAI , Walter L. JOHNSON , Yam B. POUDEL , Prasanna SIVAPRAKASAM , Patrice GILL , Andrew F. DONNELL , Murugaiah Andappan Murugaiah SUBBAIAH
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- International Application: PCT/US2021/014975 WO 20210126
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D487/04 ; A61K39/395
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS](/abs-image/US/2023/04/20/US20230118688A1/abs.jpg.150x150.jpg)
Abstract:
Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.
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