Invention Publication
- Patent Title: MULTIPARAMETER MATERIALS, METHODS AND SYSTEMS FOR BIOREACTOR GLYCATED SPECIES MANUFACTURE
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Application No.: US18283748Application Date: 2022-03-23
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Publication No.: US20240166984A1Publication Date: 2024-05-23
- Inventor: Caitlin O'MAHONY-BARTNETT , Barry J. MC CARTHY , Christopher W. RODE , Ronan HAYES , Fiona MADDEN , Jingjie MO , Francis C. MASLANKA , Kevin CLARK , Daniel A. TROUT , Pushpraj RANA , Emmanouela GRATSIA , Carl RAFFERTY , Karin M. BALSS , Olav LYNGBERG
- Applicant: JANSSEN BIOTECH, INC.
- Applicant Address: US PA Horsham
- Assignee: JANSSEN BIOTECH, INC.
- Current Assignee: JANSSEN BIOTECH, INC.
- Current Assignee Address: US PA Horsham
- International Application: PCT/US2022/021295 2022.03.23
- Date entered country: 2023-09-22
- Main IPC: C12M1/36
- IPC: C12M1/36 ; C12M1/00 ; C12M1/34 ; G16C20/20 ; G16C20/70
Abstract:
Methods for determining glycation on a molecule and/or a glycan structure on a glycosylated molecule through the use of a combination of spectroscopic analysis and chemometric modeling are described. In addition, methods and systems for producing a molecule with a desired level of glycation, including a non-glycated molecule, and/or a desired level of a glycan structure on a glycosylated molecule are described.
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