Invention Publication
- Patent Title: INDOLINE DERIVATIVES AS DDRS INHIBITORS
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Application No.: US18283851Application Date: 2022-03-25
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Publication No.: US20240217967A1Publication Date: 2024-07-04
- Inventor: Laura CARZANIGA , Fabio RANCATI , Andrea RIZZI , Nicolò IOTTI , Keith Christopher KNIGHT , Toby Matthew Grover MULLINS , Anna KARAWAJCZYK , Ben Paul WHITTAKER
- Applicant: CHIESI FARMACEUTICI S.P.A.
- Applicant Address: IT Parma
- Assignee: CHIESI FARMACEUTICI S.P.A.
- Current Assignee: CHIESI FARMACEUTICI S.P.A.
- Current Assignee Address: IT Parma
- Priority: EP 165281.3 2021.03.26
- International Application: PCT/EP2022/057939 2022.03.25
- Date entered country: 2023-09-25
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/4184 ; A61K31/437 ; A61K31/4709 ; A61K31/496 ; A61K31/4985 ; A61K31/506 ; C07D401/14 ; C07D403/14 ; C07D417/04 ; C07D487/04
Abstract:
The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.
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