Invention Publication
- Patent Title: COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION
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Application No.: US18764292Application Date: 2024-07-04
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Publication No.: US20240360115A1Publication Date: 2024-10-31
- Inventor: Jean-Simon Diallo , Christopher Noyce Boddy , Mark Dornan , Ramya Krishnan , Rozanne Arulanandam , Fabrice Le Boeuf , Jeffrey Smith , Andrew Macklin
- Applicant: Ottawa Hospital Research Institute , University of Ottawa
- Applicant Address: CA Ottawa
- Assignee: Ottawa Hospital Research Institute,University of Ottawa
- Current Assignee: Ottawa Hospital Research Institute,University of Ottawa
- Current Assignee Address: CA ON Ottawa; CA ON Ottawa
- Main IPC: C07D413/06
- IPC: C07D413/06 ; A61K31/341 ; A61K31/501 ; A61K45/06 ; A61P35/02 ; C07D207/36 ; C07D207/38 ; C07D207/456 ; C07D209/48 ; C07D231/08 ; C07D237/14 ; C07D307/30 ; C07D307/58 ; C07D307/60 ; C07D307/66 ; C07D317/64 ; C07D401/06 ; C07D403/06 ; C07D405/04 ; C07D405/06 ; C07D405/12 ; C07D409/06 ; C07D417/06 ; C07D471/04 ; C12N7/00

Abstract:
Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
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