Invention Application
- Patent Title: MODIFIED CYTOMEGALOVIRUS PROTEINS AND STABILIZED COMPLEXES
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Application No.: US18650745Application Date: 2024-04-30
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Publication No.: US20250009874A1Publication Date: 2025-01-09
- Inventor: Enrico MALITO , Sumana CHANDRAMOULI , Andrea CARFI , Matthew BOTTOMLEY
- Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
- Applicant Address: BE Rixensart
- Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee Address: BE Rixensart
- Main IPC: A61K39/245
- IPC: A61K39/245 ; A61K47/64 ; C07K14/005
Abstract:
Described are mutant, human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
Information query
