发明授权
US4459279A Retard form of pharmaceuticals with insoluble porous diffusion coatings
失效
用不溶性多孔扩散涂层阻滞形式的药物
- 专利标题： Retard form of pharmaceuticals with insoluble porous diffusion coatings
- 专利标题（中）： 用不溶性多孔扩散涂层阻滞形式的药物
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申请号： US409131申请日： 1982-08-18
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公开(公告)号： US4459279A公开(公告)日： 1984-07-10
- 发明人: Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
- 申请人： Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
- 申请人地址： DEX Ingelheim am Rhein
- 专利权人： Boehringer Ingelheim GmbH
- 当前专利权人： Boehringer Ingelheim GmbH
- 当前专利权人地址： DEX Ingelheim am Rhein
- 优先权： DEX2831164 19780715; DEX2836355 19780819; DEX2836356 19780819; DEX2836357 19780819; DEX2836358 19780819; DEX2836387 19780819; DEX2836388 19780819; DEX2836419 19780819; DEX2836477 19780819; DEX2905602 19790214
- 主分类号： A61K9/22
- IPC分类号： A61K9/22 ; A61K9/28 ; A61K9/48 ; A61K31/55 ; A61K27/12
摘要：
A pharmaceutical dosage unit retard form having a constant, pH-independent release rate of active ingredient, consisting of a core comprising an active ingredient, and a semi-permeable diffusion coating over the core, where the coating consists of a water-insoluble film-former, a water-soluble polymer and eventually an acid-insoluble polymer incorporated therein.
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