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1.发明授权
公开(公告)号：US4578264A
公开(公告)日：1986-03-25
申请号：US604830
申请日：1984-04-27
申请人： Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
发明人： Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
CPC分类号： A61K31/55 , A61K9/2853 , A61K9/2866 , A61K9/4808
摘要： This invention relates to a pharmaceutical dosage unit composition consisting essentially of a gelatin capsule containing (1) a disintegrating core comprising clonidine, said disintegrating core having a readily water-soluble coating, and (2) a plurality of non-disintegrating cores comprising clonidine, said non-disintegrating cores having a coating consisting of from 20 to 90 percent by weight of a water-insoluble film former and from 10 to 80 percent by weight of a water-soluble polymer, the diameter of each of the disintegrating and non-disintegrating cores being at least about 5 mm.
摘要翻译： 本发明涉及一种基本上由明胶胶囊组成的药物剂量单位组合物，其包含（1）包含可乐定的崩解核心，所述崩解核心具有容易水溶性的涂层，和（2）多种非崩解核心，其包含可乐定， 所述非崩解芯具有由20至90重量％的水不溶性成膜剂和10至80重量％的水溶性聚合物组成的涂层，每个分解和不分解的直径 核心至少约5mm。
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2.发明授权
公开(公告)号：US4361546A
公开(公告)日：1982-11-30
申请号：US273643
申请日：1981-06-15
申请人： Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
发明人： Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
CPC分类号： A61K31/55 , A61K9/2853 , A61K9/2866 , A61K9/4808
摘要： A pharmaceutical dosage unit retard form having a constant, pH-independent release rate of active ingredient, consisting of a core comprising an active ingredient, and a semi-permeable diffusion coating over the core, were the coating consists of a water-insoluble film-former, a water-soluble polymer and eventually an acid-insoluble polymer incorporated therein.
摘要翻译： 该涂层由水不溶性薄膜形成的药物剂量单位延迟形式具有恒定的pH独立的活性成分释放速率，由包含活性成分的核心和核心上的半渗透扩散涂层组成， 前者，水溶性聚合物和最终掺入其中的酸不溶性聚合物。
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3.发明授权
公开(公告)号：US4459279A
公开(公告)日：1984-07-10
申请号：US409131
申请日：1982-08-18
申请人： Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
发明人： Herbert Stricker , Bernhard Freund , Heribert Harwalik , Karl L. Rominger , Siegfried Darda , Volkmar Haselbarth , Dietrich Arndts , Wolf D. Bechtel , Gerhard Bozler , Rolf Brickl , Peter Gruber
CPC分类号： A61K31/55 , A61K9/2853 , A61K9/2866 , A61K9/4808
摘要： A pharmaceutical dosage unit retard form having a constant, pH-independent release rate of active ingredient, consisting of a core comprising an active ingredient, and a semi-permeable diffusion coating over the core, where the coating consists of a water-insoluble film-former, a water-soluble polymer and eventually an acid-insoluble polymer incorporated therein.
摘要翻译： 药物剂量单位延迟形式，其具有恒定的pH独立的活性成分释放速率，由包含活性成分的核心和核心上的半渗透扩散涂层组成，其中涂层由水不溶性膜 - 前者，水溶性聚合物和最终掺入其中的酸不溶性聚合物。
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4.发明授权Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof 失效二氯吡咯持续释放形式，包括漆包衣颗粒及其制备
公开(公告)号：US4367217A
公开(公告)日：1983-01-04
申请号：US221834
申请日：1980-12-31
申请人： Peter Gruber , Rolf Brickl , Gerhard Bozler , Herbert Stricker
发明人： Peter Gruber , Rolf Brickl , Gerhard Bozler , Herbert Stricker
IPC分类号： A61K9/16 , A61K9/22 , A61K9/24 , A61K9/48 , A61K9/50 , A61K9/52 , A61K9/54 , A61K9/56 , A61K31/505 , A61P9/08 , A61P9/10 , A61K9/26
CPC分类号： A61K9/5042 , A61K31/505 , A61K9/1617 , A61K9/5026 , A61K9/5078
摘要： This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating surrounding said spheroid particles, said coating being comprised of from about 50 to 100 percent by weight of acid-insoluble lacquers soluble in intestinal juices and from about 0 to 50 percent by weight of lacquers insoluble in gastric and intestinal juices and said coating being present in an amount of from about 3 to 30 percent by weight, based on the weight of the spheroid particles, and to the preparation of such a composition.
摘要翻译： 本发明涉及用于缓释双嘧达莫的组合物，其包括（i）由双嘧达莫或其结晶盐和药理学上可接受的酸或酸性物质组成的球状颗粒，和（ii）围绕所述球状颗粒的涂层，所述涂层由 约50至100重量％的可溶于肠液的酸不溶性漆和约0至50重量％不溶于胃肠和肠液的漆，并且所述涂层以约3至30重量％的量存在， 重量，基于球状颗粒的重量，以及这种组合物的制备。
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公开(公告)号：US5633002A
公开(公告)日：1997-05-27
申请号：US434828
申请日：1995-05-04
CPC分类号： A61K9/0024 , A61K9/2013 , A61K9/204
摘要： The invention relates to an implantable biodegradable system for releasing active substance.
摘要翻译： 本发明涉及一种用于释放活性物质的可植入式可生物降解的系统。
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公开(公告)号：US10669162B2
公开(公告)日：2020-06-02
申请号：US14509088
申请日：2014-10-08
申请人： Herbert Stricker
发明人： Herbert Stricker
摘要： The present disclosure relates to a portable water filter kit including a portable housing unit with an interior space. The portable housing unit includes an input nozzle and an output nozzle for connecting to a hose, piping between the input and output nozzle located in the interior of the portable housing unit, and a filter. The portable water filter kit is configured such that all components may be stored in the interior space of the portable housing unit.
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公开(公告)号：USD644897S1
公开(公告)日：2011-09-13
申请号：US29386413
申请日：2011-02-28
申请人： Herbert Stricker
设计人： Herbert Stricker
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8.发明授权Process for preparing poly-D,L-lactide and the use thereof as a carrier for active substances 失效制备聚-D，L-丙交酯的方法及其作为活性物质载体的用途
公开(公告)号：US5302693A
公开(公告)日：1994-04-12
申请号：US717562
申请日：1991-06-19
申请人： Herbert Stricker , Dieter Bendix
发明人： Herbert Stricker , Dieter Bendix
CPC分类号： A61K9/0024 , A61K9/204 , C08G63/08
摘要： The invention relates to a process for preparing poly-D,L-lactide and its use as a carrier for active substances.
摘要翻译： 本发明涉及一种制备聚-D，L-丙交酯及其用作活性物质载体的方法。
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公开(公告)号：US20190256370A9
公开(公告)日：2019-08-22
申请号：US14509088
申请日：2014-10-08
申请人： Herbert Stricker
发明人： Herbert Stricker
IPC分类号： C02F1/00
摘要： The present disclosure relates to a portable water filter kit including a portable housing unit with an interior space. The portable housing unit includes an input nozzle and an output nozzle for connecting to a hose, piping between the input and output nozzle located in the interior of the portable housing unit, and a filter. The portable water filter kit is configured such that all components may be stored in the interior space of the portable housing unit.
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公开(公告)号：US20190092648A1
公开(公告)日：2019-03-28
申请号：US14509088
申请日：2014-10-08
申请人： Herbert Stricker
发明人： Herbert Stricker
IPC分类号： C02F1/00
摘要： The present disclosure relates to a portable water filter kit including a portable housing unit with an interior space. The portable housing unit includes an input nozzle and an output nozzle for connecting to a hose, piping between the input and output nozzle located in the interior of the portable housing unit, and a filter. The portable water filter kit is configured such that all components may be stored in the interior space of the portable housing unit.
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